22854-00-8

Basic information

• Product Name: 2-methyl-(1,2-dideoxy-α-D-glucopyranoso)-[2,1-d]-2-oxazoline
• Synonyms: 2-methyl-(1,2-dideoxy-α-D-glucopyranoso)-[2,1-d]-2-oxazoline
• CAS NO: 22854-00-8
• Molecular Weight: 203.195
• Mol File: 22854-00-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-(1,2-dideoxy-α-D-glucopyranoso)-[2,1-d]-2-oxazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-(1,2-dideoxy-α-D-glucopyranoso)-[2,1-d]-2-oxazoline(22854-00-8)
• EPA Substance Registry System: 2-methyl-(1,2-dideoxy-α-D-glucopyranoso)-[2,1-d]-2-oxazoline(22854-00-8)

Safety Data

• Hazardous Substances Data: 22854-00-8(Hazardous Substances Data)

Upstream product

• 7512-17-6 N-Acetyl-D-glucosamine 

Downstream Products

• 29847-23-2 2-N-acetylamido-2-deoxy-β-D-glucopyranosyl azide 
• 4171-78-2 2-acetamido-1-O-benzoyl-2-deoxy-β-D-glucopyranose 
• 74034-09-6 2-acetamido-1,5-anhydro-4,6-O-benzylidene-2-deoxy-D-glucitol 
• 52659-32-2 2,4-Dinitrophenyl-2-acetamido-2-deoxy-β-D-glucopyranosid 
• 3459-18-5 4-nitrophenyl N-acetyl-β-D-glucosaminide 
• 5574-80-1 phenyl 2-acetamido-2-deoxy-β-D-glucopyranoside 
• 3946-01-8 methyl N-acetyl-β-D-glucosaminide 

Relevant articles and documents

Protecting-group-free one-pot synthesis of glycoconjugates directly from reducing sugars

The conversion of sugars into glycomimetics typically involves multiple protecting-group manipulations. The development of methodology allowing the direct aqueous conversion of free sugars into glycosides, and mimics of oligosaccharides and glycoconjugates in a high-yielding and stereoselective process is highly desirable. The combined use of 2-azido-1,3-dimethylimidazolinium hexafluorophosphate and the Cu-catalyzed Huisgen cycloaddition allowed the synthesis of a range of glycoconjugates in a one-step reaction directly from reducing sugars under aqueous conditions. The reaction, which is completely stereoselective, may be applied to the convergent synthesis of triazole-linked glycosides, oligosaccharides, and glycopeptides. The procedure provides a method for the one-pot aqueous ligation of oligosaccharides and peptides bearing alkyne side chains.