22894-90-2

Basic information

• Product Name: Benzene, 1-[(4-methoxyphenyl)thio]-2-methyl-
• CAS NO: 22894-90-2
• Molecular Formula: C14H14OS
• Molecular Weight: 230.331
• Mol File: 22894-90-2.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzene, 1-[(4-methoxyphenyl)thio]-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-[(4-methoxyphenyl)thio]-2-methyl-(22894-90-2)
• EPA Substance Registry System: Benzene, 1-[(4-methoxyphenyl)thio]-2-methyl-(22894-90-2)

Safety Data

• Hazardous Substances Data: 22894-90-2(Hazardous Substances Data)

Upstream product

• 696-62-8 para-iodoanisole 
• 100-17-4 para-methoxynitrobenzene 
• 137-06-4 2-thiocresol 
• 1950-68-1 4-methoxybenzenesulfonyl hydrazide 
• 16419-60-6 2-Methylphenylboronic acid 
• 4032-80-8 bis(2-methylphenyl)disulfide 
• 5720-07-0 4-methoxyphenylboronic acid 
• 696-63-9 4-Methoxybenzenethiol 
• 635-26-7 o-tolylhydrazine hydrochloride 
• 24022-34-2 dithiocarbonic acid O-ethyl ester-S-o-tolyl ester 
• 529-27-1 2-methylphenylhydrazine 
• 623-12-1 4-chloromethoxybenzene 
• 794-94-5 p-Methoxybenzoic anhydride 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 

Downstream Products

• 92190-63-1 1-((4-methoxyphenyl)sulfonyl)-2-methylbenzene 

Relevant articles and documents

Ni-catalyzed C–S bond cleavage of aryl 2-pyridyl thioethers coupling with alkyl and aryl thiols

A nickel-catalyzed C–SPy bond activation reactions to produce a variety of thioethers has been developed. The reaction is promoted by a user-friendly, inexpensive, air and moisture-stable Ni precatalyst. Various aryl 2-pyridyl thioethers and a wide range of alkyl and aryl thiols substrates were tolerated in this process which afforded products in moderate to excellent yields.

Thiol Activation toward Selective Thiolation of Aromatic C-H Bond

Direct C-S bond coupling is an attractive way to construct aryl sulfur ether, a building block for a variety of biological active molecules. Herein, we disclose an effective model for regioselective thiolation of the aromatic C-H bond by thiol activation instead of arene activation. Strikingly, this method has been applied into anisole derivatives that are not available in the arene activation approach to forge a single thioether isomer with high reactivity.

Forging C-S Bonds through Nickel-Catalyzed Aryl Anhydrides with Thiophenols: Decarbonylation or Decarbonylation Accompanied by Decarboxylation

A nickel-catalyzed decarbonylation or decarbonylation accompanied by decarboxylation cross-coupling reaction of aryl anhydrides with thiophenols as coupling partners was disclosed. This method is promoted by a commercially available, moisture-stable, and inexpensive nickel(II) precatalyst. The process can tolerate a variety of functional groups using ubiquitous aryl anhydrides as cross-coupling precursors to produce thioethers in moderate to excellent yields.