229177-79-1

Basic information

• Product Name: (R)-(+)-2,2'-BIS(N-DIPHENYLPHOSPHINOAMINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL
• Synonyms: CTH-(S)-BINAM;CTH-(R)-BINAM;(S)-(-)-2,2'-BIS(N-DIPHENYLPHOSPHINOAMINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL;(R)-(+)-2,2'-BIS(N-DIPHENYLPHOSPHINOAMINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL;min.cth-(s)-binam;(S)-(-)-2,2'-Bis(N-diphenylphosphinoamino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl,min.95%CTH-(S)-BINAM;(s)-(-)-2,2'-bis(n-diphenylphosphinoamino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl, cth-(s)-binam;(S)-(-)-2,2'-Bis(N-diphenylphosphinoamino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl Application: Asymmetric hydrogenation Store N2Ar
• CAS NO: 229177-79-1
• Molecular Formula: C44H42N2P2
• Molecular Weight: 660.77
• Product Categories: Achiral Nitrogen;BINAM Series
• Mol File: 229177-79-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 787.1°Cat760mmHg
• Flash Point: 429.8°C
• Appearance: white/solid
• Density: g/cm³
• CAS DataBase Reference: (R)-(+)-2,2'-BIS(N-DIPHENYLPHOSPHINOAMINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-2,2'-BIS(N-DIPHENYLPHOSPHINOAMINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL(229177-79-1)
• EPA Substance Registry System: (R)-(+)-2,2'-BIS(N-DIPHENYLPHOSPHINOAMINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL(229177-79-1)

Safety Data

• Hazardous Substances Data: 229177-79-1(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 208248-66-2 5,6,7,8,5',6',7',8'-octahydro-[1,1']binaphthalenyl-2,2'-diamine 
• 4488-22-6 1,1'-binaphthalene-2,2'-diamine 

Relevant articles and documents

A comparison of the asymmetric hydrogenation catalyzed by rhodium complexes containing chiral ligands with a binaphthyl unit and those with a 5,5′,6,6′,7,7′,8,8′-octahydro-binaphthyl unit

The chiral ligands H8-BINAPO and H8-BDPAB were synthesized by reacting chlorodiphenylphosphine with H8-BINOL and H8-BINAM, respectively. Applications of these ligands in the Rh-catalyzed enantioselective hydrogenation of a variety of (Z)-acetamido-3-arylacrylic acid methyl esters provided chiral amino acid derivatives with good to excellent enantioselectivities (H8-BINAPO: up to 84.0% e.e.; H8-BDPAB: up to 97.1% e.e.). In the hydrogenation of acetamidoacrylic acid, 99% e.e. was obtained when a [Rh(H8-BDPAB)]+ catalyst was used. The catalytic activities and enantioselectivities of [Rh(H8-BINAPO)]+ and [Rh(H8-BDPAB]+ are substantially better than those obtained with the corresponding rhodium catalysts containing BINAPO (up to 64% e.e.) and BDPAB (up to 92.6% e.e.).