22930-75-2

Basic information

• Product Name: 3-METHYL-1H-PYRROLO[3,2-C]PYRIDINE
• Synonyms: 3-METHYL-1H-PYRROLO[3,2-C]PYRIDINE;3-Methyl-5-azaindole;3-Methyl-5-azaindole 3-Methyl-1H-pyrrolo[3,2-c]pyridine;1H-Pyrrolo[3,2-c]pyridine, 3-methyl-
• CAS NO: 22930-75-2
• Molecular Formula: C₈H₈N₂
• Molecular Weight: 132.165
• Mol File: 22930-75-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 138-140 °C
• Boiling Point: 286.4±20.0 °C(Predicted)
• Appearance: /
• Density: 1.186±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 15.50±0.40(Predicted)
• CAS DataBase Reference: 3-METHYL-1H-PYRROLO[3,2-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-1H-PYRROLO[3,2-C]PYRIDINE(22930-75-2)
• EPA Substance Registry System: 3-METHYL-1H-PYRROLO[3,2-C]PYRIDINE(22930-75-2)

Safety Data

• Hazardous Substances Data: 22930-75-2(Hazardous Substances Data)

Usage

General Description

3-METHYL-1H-PYRROLO[3,2-C]PYRIDINE, also known as 1-Methyl-5H-pyrrolo[3,2-c]pyridine, is a heterocyclic compound with the molecular formula C9H7N. It is a derivative of pyridine and contains a pyrrole ring fused to a pyridine ring, with a methyl group attached to the nitrogen atom. 3-METHYL-1H-PYRROLO[3,2-C]PYRIDINE is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and bioactive molecules. It exhibits biological activity and has been studied for its potential medicinal properties, including its antiviral and anti-tumor effects. Additionally, 3-METHYL-1H-PYRROLO[3,2-C]PYRIDINE has been investigated for its use in organic synthesis and material science applications.

Upstream product

• 868173-90-4 3-methyl-2-trimethylsilyl-1H-pyrrolo[3,2-c]pyridine 
• 88511-27-7 3-iodopyridin-4-amine 

Downstream Products

• 868173-98-2 N-[4-(3-methyl-pyrrolo[3,2-c]pyridine-1-sulfonyl)-phenyl]-acetamide 

Relevant articles and documents

TRIAZINE COMPOUND AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

The invention discloses a triazine derivative and a pharmaceutically acceptable salt, a pharmaceutical composition and use thereof. Particularly, the invention discloses a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3 and R4 are defined as described in the description and claims. The compound or a salt thereof according to the invention may be used for treating or preventing diseases or conditions by regulating some mutation forms of epidermal growth factor receptors. The invention also discloses a pharmaceutical composition comprising the compound or a salt thereof, and a method for treating various forms of EGFR-mediated diseases (including non-small cell lung cancer) by using the compound and a salt thereof.

diazaindenes (azaindoles)-IV. Oxidation of 1,5- and 1,7-diazaindenes and a novel route to 3-substituted diazaindenes

Treatment of certain 1,5- and 1,7-diazaindenes with a small molar excess of hydrogen peroxide in acetic acid causes opening of the pyrrole ring with loss of the 2-C atom to give aminopyridyl ketones or aminopyridine carboxylic acids. The former have been used as intermediates in the synthesis of 3-substituted diazaindenes by reaction with dimethylsulphonium methylide. Stable iodine complexes with 1,5-diazaindenes may be formed: 6-(4-aminopyrid-3-yl)-6-oxohexanoic acid gave 4-(1-methyl-1,5-diazainden-3-yl)butanoic acid.