22955-75-5

Basic information

• Product Name: 3-(2-METHOXY-PHENYL)-PROPIONYL CHLORIDE
• Synonyms: 3-(2-METHOXY-PHENYL)-PROPIONYL CHLORIDE
• CAS NO: 22955-75-5
• Molecular Formula: C₁₀H₁₁ClO₂
• Molecular Weight: 198.65
• Mol File: 22955-75-5.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(2-METHOXY-PHENYL)-PROPIONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-METHOXY-PHENYL)-PROPIONYL CHLORIDE(22955-75-5)
• EPA Substance Registry System: 3-(2-METHOXY-PHENYL)-PROPIONYL CHLORIDE(22955-75-5)

Safety Data

• Hazardous Substances Data: 22955-75-5(Hazardous Substances Data)

Upstream product

• 6342-77-4 2-methoxy-benzenepropanoic acid 
• 1011-54-7 2-methoxycinnamic acid 
• 135-02-4 ortho-anisaldehyde 
• 93-25-4 2-methoxyphenylacetic acid 
• 124067-29-4 3-(2-anisyl)-α-diazo-2-propanone 
• 121985-99-7 2-hydroxy-2-(2-methoxyphenyl)acetonitrile 
• 90-02-8 salicylaldehyde 
• 28033-63-8 2-(2-methoxyphenyl)acetyl chloride 
• 6099-03-2 3-(2'-methoxyphenyl)propenoic acid 

Downstream Products

• 101499-64-3 5-(2-methoxy-phenyl)-2-methyl-3-oxo-valeric acid ethyl ester 
• 33538-83-9 3-(2-methoxyphenyl)propanal 
• 109089-84-1 3-(2-methoxyphenyl)-1-(4-methoxyphenyl)propan-1-one 
• 90266-01-6 1-diazo-4-(2'-methoxyphenyl)butan-2-one 
• 148728-43-2 1-<3-(2-methoxyphenyl)-1-oxopropyl>piperazine 
• 107025-52-5 N-Methoxy-3-(2-methoxy-phenyl)-propionamide 
• 32940-15-1 5-methoxy-2-tetralone 
• 5309-19-3 8-methoxy-2-tetralone 
• 3880-77-1 8-methoxy-2-aminotetralin 
• 81185-19-5 N-benzyl-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine 
• 148728-44-3 1-(2-chloro-1-oxoethyl)-4-(3-<2-methoxyphenyl>propyl)piperazine 
• 148728-45-4 1-<3-(2-methoxyphenyl)propyl>-4-<1-oxo-2-<(2-phenoxyphenyl)methoxy>ethyl>piperazine 

Relevant articles and documents

Ruthenium-catalyzed intramolecular arene C(sp2)-H amidation for synthesis of 3,4-dihydroquinolin-2(1 H)-ones

We report the [Ru(p-cymene)(l-proline)Cl] ([Ru1])-catalyzed cyclization of 1,4,2-dioxazol-5-ones to form dihydroquinoline-2-ones in excellent yields with excellent regioselectivity via a formal intramolecular arene C(sp2)-H amidation. The reactions of the 2- and 4-substituted aryl dioxazolones proceeds initially through spirolactamization via electrophilic amidation at the arene site, which is para or ortho to the substituent. A Hammett correlation study showed that the spirolactamization is likely to occur by electrophilic nitrenoid attack at the arene, which is characterized by a negative ρ value of -0.73.

Rh(III)-Catalyzed meta-C-H Olefination Directed by a Nitrile Template

A range of Rh(III)-catalyzed ortho-C-H functionalizations have been developed; however, extension of this reactivity to remote C-H functionalizations through large-ring rhodacyclic intermediates has yet to be demonstrated. Herein we report the first examp

An investigation into the electrophilic cyclisation of N-acyl-pyrrolidinium ions: A facile synthesis of Pyrrolo-tetrahydroisoquinolones and Pyrrolo-benzazepinones

The triflic acid-mediated cyclisation of N-arylmethyl- and N-arylethyl-acylpyrrolidinium ions gave moderate to good yields of pyrrolo-tetrahydroisoquinolones and pyrrolo-benzazepinones respectively. Electron-donating R substituents enhanced the rate of reaction and gave higher yields than electron-withdrawing substituents. Substituents on the methyl or ethyl chain in general enhanced the reaction, unless sterically encumbered. The equivalent acylpiperidinium ions cyclised much slower and in lower yield.