229646-37-1

Basic information

• Product Name: 4-(6-Chloronaphthalen-2-ylsulfonyl)-1-[1-(4-pyridyl)piperidin-4-ylmethyl]piperazin-2-one
• Synonyms: M-55113
• CAS NO: 229646-37-1
• Molecular Formula: C₂₅H₂₇ClN₄O₃S
• Molecular Weight: 499.03594
• Mol File: 229646-37-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(6-Chloronaphthalen-2-ylsulfonyl)-1-[1-(4-pyridyl)piperidin-4-ylmethyl]piperazin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(6-Chloronaphthalen-2-ylsulfonyl)-1-[1-(4-pyridyl)piperidin-4-ylmethyl]piperazin-2-one(229646-37-1)
• EPA Substance Registry System: 4-(6-Chloronaphthalen-2-ylsulfonyl)-1-[1-(4-pyridyl)piperidin-4-ylmethyl]piperazin-2-one(229646-37-1)

Safety Data

• Hazardous Substances Data: 229646-37-1(Hazardous Substances Data)

Upstream product

• 102153-63-9 6-chloronaphth-2-ylsulfonyl chloride 
• 229647-14-7 1-[[1-(4-pyridinyl)-4-piperidinyl]methyl]piperazinone 
• 130658-67-2 4-hydroxymethyl-1-(pyridin-4-yl)piperidine 
• 229647-08-9 1-(4-pyridinyl)-4-piperidinecarboxaldehyde 
• 239073-00-8 4-Benzyloxycarbonyl-1,2,3,4-tetrahydropyrazin-2-one 
• 239074-30-7 1-(pyridin-4-yl)-4-methylsulfonyloxymethylpiperidine 
• 7440-05-3 palladium 

Relevant articles and documents

Sulfonamide derivatives, processes for producing the same and utilization thereof

The present invention is to provide a compound or a salt thereof represented by the formula: wherein R1is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, the ring A is an optionally substituted divalent nitrogen-containing heterocyclic group, X′ is an optionally substituted alkylene chain, Y is an optionally substituted divalent cyclic group, X is a chemical bond or an optionally substituted alkylene chain, and Z is (1) an optionally substituted amino group, (2) an optionally substituted imidoyl group or (3) an optionally substituted nitrogen-containing heterocyclic group, or a pro-drug thereof, which have activated coagulation factor X inhibitory activity and which are useful as anti-coagulants.

AROMATIC COMPOUNDS HAVING CYCLIC AMINO OR SALTS THEREOF

Compounds represented by general formula (I) or salts thereof which specifically inhibit FXa, exert a potent anticoagulant effect and thus are useful as medicinal compositions, wherein G1 to G4, X and Y represent each CH or N; Z1 represents -SO2- or -CH2 -; Q represents aryl or heteroaryl; and R1 to R9 represent each hydrogen or a substituent.