23000-11-5 Usage
Physical form
Yellow crystalline solid
Uses
Metabolic uncoupler in biochemical research, pesticide
Mechanism of action
Disrupts oxidative phosphorylation in mitochondria, leading to dissipation of proton gradient and production of heat instead of ATP
Effects on body
Induces weight loss and increases metabolic rate
Toxicity
Significant, with potential for severe side effects including hyperthermia, organ failure, and death
Legal status
Not approved for human consumption or use
Check Digit Verification of cas no
The CAS Registry Mumber 23000-11-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,0,0 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 23000-11:
(7*2)+(6*3)+(5*0)+(4*0)+(3*0)+(2*1)+(1*1)=35
35 % 10 = 5
So 23000-11-5 is a valid CAS Registry Number.
23000-11-5Relevant articles and documents
Inhibitors of inosine monophosphate dehydrogenase: SARs about the N-[3-methoxy-4-(5-oxazolyl)phenyl moiety
Iwanowicz, Edwin J.,Watterson, Scott H.,Guo, Junqing,Pitts, William J.,Murali Dhar,Shen, Zhongqi,Chen, Ping,Gu, Henry H.,Fleener, Catherine A.,Rouleau, Katherine A.,Cheney, Daniel L.,Townsend, Robert M.,Hollenbaugh, Diane L.
, p. 2059 - 2063 (2007/10/03)
The first reported structure-activity relationships (SARs) about the N-[3-methoxy-4-(5-oxazolyl)phenyl moiety for a series of recently disclosed inosine monophosphate dehydrogenase (IMPDH) inhibitors are described. The syntheses and in vitro inhibitory values for IMPDH II, and T-cell proliferation (for select analogues) are given.
