2303-80-2

Basic information

• Product Name: (5R)-5-ethyl-1-methyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione
• Synonyms: 2,4,6(1H,3H,5H)-pyrimidinetrione, 5-ethyl-1-methyl-5-phenyl-, (5R)-
• CAS NO: 2303-80-2
• Molecular Formula: C₁₃H₁₄N₂O₃
• Molecular Weight: 246.2619
• Mol File: 2303-80-2.mol
• Article Data: 4

Chemical Properties

• Density: 1.211g/cm³
• Refractive Index: 1.543
• CAS DataBase Reference: (5R)-5-ethyl-1-methyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-5-ethyl-1-methyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione(2303-80-2)
• EPA Substance Registry System: (5R)-5-ethyl-1-methyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione(2303-80-2)

Safety Data

• Hazardous Substances Data: 2303-80-2(Hazardous Substances Data)

Upstream product

• 165131-08-8 (5S)-5-ethyl-3-methyl-1-(methyl β-D-glucopyranosyluronate)-5-phenyl-2,4,6-(1H,3H,5H)-pyrimidinetrione 
• 115-38-8 mephobarbital 
• 164669-88-9 (5S)-5-ethyl-1-(methyl β-D-glucopyranosyluronate)-5-phenyl-2,4,6-(1H,3H,5H)-pyrimidinetrione 
• 50-06-6 phenobarbital 
• 138548-35-3 (S)(+)-5-ethyl-5-phenyl-1-(propionyloxymethyl)barbital 
• 27506-81-6 1,3-bis(propionyloxymethyl)-5-ethyl-5-phenylbarbital 

Relevant articles and documents

Direct gaschromatographic separation of drug racemates

For inspection of the direct separability of synthetic drug racemates through GC/MS a uniform scheme is proposed and checked with 35 drugs and two cyclodextrin capillary columns. All investigated analytes vaporized without decomposition, 26 of them are separable in the enantiomers, among them 10 with separation to the baseline and 14 with CO-NH-structure.

Lipase-catalyzed enantioselective synthesis of optically active mephrobarbital, hexobarbital and febarbamate

Chiral 5,5-disubstituted N-acyloxymethylbarbiturates have been obtained in 40-99% optical yields by lipase-catalyzed hydrolyses of 5,5-disubstituted N,N'-bisacyloxymethylbarbiturates in H2O-saturated diisopropyl ether. These chiral barbiturates