230310-66-4

Basic information

• Product Name: (2-dibenzofuranyl)-diphenylphosphine
• Synonyms: (2-dibenzofuranyl)-diphenylphosphine
• CAS NO: 230310-66-4
• Molecular Weight: 352.372
• Mol File: 230310-66-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2-dibenzofuranyl)-diphenylphosphine(CAS DataBase Reference)
• NIST Chemistry Reference: (2-dibenzofuranyl)-diphenylphosphine(230310-66-4)
• EPA Substance Registry System: (2-dibenzofuranyl)-diphenylphosphine(230310-66-4)

Safety Data

• Hazardous Substances Data: 230310-66-4(Hazardous Substances Data)

Upstream product

• 86-76-0 2-bromodibenzo[b,d]furan 
• 1079-66-9 chloro-diphenylphosphine 
• 132-64-9 dibenzofuran 
• 122948-59-8 2-(trifluoromethanesulfonyloxy)dibenzofuran 
• 829-85-6 diphenylphosphane 

Relevant articles and documents

Synthesis of the dibenzofuran-based diphosphine ligand BIFAP and its water-soluble derivative BIFAPS and their use in ruthenium-catalyzed asymmetric hydrogenation

The syntheses of both enantiomers of the novel diphosphine ligand 2,2′-bis(diphenylphosphanyl)-1,1′-bidibenzofuranyl (BIFAP, 1) and the water-soluble analogue (-)-2,2′-bis(diphenylphosphanyl)-1,1′-bidibenzofuranyl-8,8′- disulfonic acid dipotassium salt (BIFAPS, 2) are reported. Advantage is taken of the very high regioselectivity in ring functionalisation of the 1,1′-bidibenzofuranyl backbone. These ligands are used in the ruthenium-catalysed hydrogenation of methyl acetoacetate and (Z)-acetamidocinnamic acid in methanol and water. In methanol both BIFAP and BIFAPS give the products in very high enantiomeric excess. With BIFAPS in water a slight drop in the ee of the products is observed. When BIFAPS is used with either water or methanol as the solvent the addition of a small amount of acid turns out to be essential for a fast reaction and high asymmetric induction.