230631-31-9Relevant articles and documents
XYLO-LNA ANALOGUES
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Page/Page column 21-22, (2010/05/13)
A bicyclic nucleoside derivative, wherein an intranucleoside ring locks the ring conformation of the nucleoside, is termed an LNA - a Locked Nucleic Acid. LNAs of the xylo-configuration, considered useful as therapeutic agents, diagno
Synthesis of 5-Azacytidine nucleosides with rigid sugar moiety as potential antitumor agents
Chun, Moon Woo,Kim, Myong Jung,Kim, Hea Ok,Kim, Hee-Doo,Kim, Joong Hyup,Moon, Hyung Ryong,Jeong, Lak Shin
, p. 915 - 917 (2007/10/03)
The bicyclic 3′-O,5′-C-methylene-linked and 2′-O,5′-C-methylene-linked 5-azacytidine derivatives were readily synthesized from 1,2;5,6-di-O-isopropylidene-D-glucose and evaluated against several cancer cell lines.