23068-45-3

Basic information

• Product Name: butyl(2-phenylethyl)amine
• Synonyms: butyl(2-phenylethyl)amine
• CAS NO: 23068-45-3
• Molecular Formula: C₁₂H₁₉N
• Molecular Weight: 177.28596
• Mol File: 23068-45-3.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• CAS DataBase Reference: butyl(2-phenylethyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: butyl(2-phenylethyl)amine(23068-45-3)
• EPA Substance Registry System: butyl(2-phenylethyl)amine(23068-45-3)

Safety Data

• Hazardous Substances Data: 23068-45-3(Hazardous Substances Data)

Upstream product

• 22871-49-4 N-butyl-2-phenylethanethioamide 
• 123-72-8 butyraldehyde 
• 64-04-0 phenethylamine 
• 71-36-3 butan-1-ol 
• 90496-15-4 N-Butyliden-β-phenaethylamin 
• 6283-13-2 N-(2-phenylethyl)butanamide 
• 110-68-9 N-n-butyl-N-methylamine 
• 100-39-0 benzyl bromide 
• 119437-45-5 N-butyl-N-(2-phenylethyl)-9-aminofluorene 
• 115419-45-9 β-phenylethyldiphenylbismuth 
• 109-73-9 N-butylamine 
• 115419-46-0 tris-β-phenylethylbismuth 
• 109-65-9 1-bromo-butane 
• 119437-41-1 N-(2-phenylethyl)-9H-fluoren-9-imine 

Downstream Products

• 24068-19-7 butyl-diphenethyl-amine 
• 6121-14-8 1-Butyl-1-phenaethyl-biuret 
• 5779-51-1 N-butyl-N-phenethylbutan-1-amine 
• 1352347-53-5 N-ethyl-N-pentyl-2-phenethylamine 
• 66887-15-8 N-butyl-N-phenethylacetamide 

Relevant articles and documents

A BEt3-Base catalyst for amide reduction with silane

Reported herein is the development of a simple but practical catalytic system for the selective reduction of amides with hydrosilane or hydrosiloxane. Low-cost and readily available triethylborane (1.0 M in THF), in combination with a catalytic amount of an alkali metal base, was found to catalyze the reduction of all three amide classes (tertiary, secondary, and primary amides) to form amines under mild conditions. In addition, the selective transformation of secondary amides to aldimines and primary amides to nitriles can also be achieved by using a proper combination of BEt3 and base. The scope of these BEt3-base-catalyzed amide hydrosilylation reactions has been explored in depth. Preliminary results of mechanistic studies suggest a modified Piers' silane Si-H···B activation mode wherein the hydride abstraction by BEt3 is promoted by the coordination of an alkoxide or hydroxide anion to the Si center.

Direct Reductive N-Functionalization of Aliphatic Nitro Compounds

The first general protocol for the direct reductive N-functionalization of aliphatic nitro compounds is presented. The nitro group is partially reduced to a nitrenoid, with a mild and readily available combination of B2pin2 and zinc organyls. Thereby, the formation of an unstable nitroso intermediate is avoided, which has so far severely limited reductive transformations of aliphatic nitro compounds. The reaction is concluded by an electrophilic amination of zinc organyls.

Ruthenium-catalyzed N-alkylation of amines with alcohols under mild conditions using the borrowing hydrogen methodology

Using a simple amino amide ligand, ruthenium-catalyzed one-pot alkylation of primary and secondary amines with simple alcohols was carried out under a wide range of conditions. Using the alcohol as solvent, alkylation was achieved under mild conditions, even as low as room temperature. Reactions occurred with high conversion and selectivity in many cases. Reactions can also be carried out at high temperatures in organic solvent with high selectivity using stoichiometric amounts of the alcohol.