23081-78-9

Basic information

• Product Name: 2-Pyridinylphosphonic acid diethyl ester
• Synonyms: 2-Pyridinylphosphonic acid diethyl ester
• CAS NO: 23081-78-9
• Molecular Formula: C₉H₁₄NO₃P
• Molecular Weight: 0
• Mol File: 23081-78-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyridinylphosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinylphosphonic acid diethyl ester(23081-78-9)
• EPA Substance Registry System: 2-Pyridinylphosphonic acid diethyl ester(23081-78-9)

Safety Data

• Hazardous Substances Data: 23081-78-9(Hazardous Substances Data)

Upstream product

• 53920-49-3 N-methoxypyridinium p-toluenesulfonate 
• 762-04-9 phosphonic acid diethyl ester 

Downstream Products

• 5058-19-5 2-butylpyridine 
• 5683-33-0 2-(Dimethylamino)pyridine 
• 125995-87-1 3-Phenyl-3-(pyridin-2-ylphosphanyl)-propionic acid methyl ester 
• 1586007-07-9 C₃₄H₃₂N₃P 
• 1586007-05-7 C₄₀H₃₈N₄P₂ 
• 1586007-06-8 C₂₈H₃₀N₄P₂ 
• 1586025-00-4 C₂₈H₃₀Cl₂N₄P₂Pt 
• 1586025-01-5 C₂₈H₃₀Cl₂N₄P₂Pt 
• 1586025-02-6 C₂₈H₃₀Cl₂N₄P₂Pd 
• 1586007-04-6 C₂₈H₃₀N₄P₂ 
• 1439809-15-0 1,5-bis(p-tolyl)-3,7-bis(pyridine-2-yl)-1,5-diaza-3,7-diphosphacyclooctane 

Relevant articles and documents

2-Pyridylphosphonates: A new type of modification for nucleotide analogues

Suitably protected dithymidine H-phosphonates afforded the corresponding dinucleoside 2-pyridylphosphonates upon treatment with N-methoxypyridinium tosylate in acetonitrile in the presence of 1,8-diazabicylo[5.4.0]undec-7-ene (DBU). The reaction was rapid (ca. 5 min), practically quantitative and proceeded stereospecifically, most likely with retention of configuration at the phosphorus centre.