23088-42-8 Usage
Description
(1-BROMOETHYL-2,2,2-D3)BENZENE, also known as (±)-(1-Bromoethyl-2,2,2-d3)benzene, is an isotopically labeled research compound with the chemical formula C8D3BrH9. It is characterized by the presence of deuterium atoms (2H or D), which are stable isotopes of hydrogen, and a bromine atom (Br) attached to an ethyl group. (1-BROMOETHYL-2,2,2-D3)BENZENE is primarily used in scientific research and development.
Uses
Used in Research and Development:
(1-BROMOETHYL-2,2,2-D3)BENZENE is used as an isotopically labeled research compound for various applications in scientific research. The incorporation of deuterium atoms allows for the study of chemical reactions and processes with enhanced sensitivity and accuracy. (1-BROMOETHYL-2,2,2-D3)BENZENE is particularly useful in fields such as organic chemistry, biochemistry, and materials science, where the understanding of reaction mechanisms and the development of new compounds are crucial.
Used in Organic Chemistry:
In the field of organic chemistry, (1-BROMOETHYL-2,2,2-D3)BENZENE is used as a reagent or intermediate in the synthesis of various organic compounds. The presence of the bromine atom and the deuterium-labeled ethyl group makes it a versatile building block for the preparation of complex organic molecules, which can be further modified or functionalized to obtain desired properties.
Used in Biochemistry:
(1-BROMOETHYL-2,2,2-D3)BENZENE can be employed in biochemistry for the study of enzyme mechanisms, metabolic pathways, and the development of novel bioactive compounds. The deuterium labeling allows for the investigation of enzyme kinetics and the elucidation of reaction mechanisms, which can lead to a better understanding of biological processes and the design of more effective drugs.
Used in Materials Science:
In materials science, (1-BROMOETHYL-2,2,2-D3)BENZENE can be utilized in the development of new materials with unique properties. The incorporation of deuterium atoms can affect the physical and chemical properties of the resulting materials, such as their stability, solubility, and reactivity. This can lead to the creation of advanced materials for various applications, including pharmaceuticals, coatings, and sensors.
Check Digit Verification of cas no
The CAS Registry Mumber 23088-42-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,0,8 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 23088-42:
(7*2)+(6*3)+(5*0)+(4*8)+(3*8)+(2*4)+(1*2)=98
98 % 10 = 8
So 23088-42-8 is a valid CAS Registry Number.
23088-42-8Relevant articles and documents
Thiourea-Mediated Halogenation of Alcohols
Mohite, Amar R.,Phatake, Ravindra S.,Dubey, Pooja,Agbaria, Mohamed,Shames, Alexander I.,Lemcoff, N. Gabriel,Reany, Ofer
supporting information, p. 12901 - 12911 (2020/11/26)
The halogenation of alcohols under mild conditions expedited by the presence of substoichiometric amounts of thiourea additives is presented. The amount of thiourea added dictates the pathway of the reaction, which may diverge from the desired halogenation reaction toward oxidation of the alcohol, in the absence of thiourea, or toward starting material recovery when excess thiourea is used. Both bromination and chlorination were highly efficient for primary, secondary, tertiary, and benzyl alcohols and tolerate a broad range of functional groups. Detailed electron paramagnetic resonance (EPR) studies, isotopic labeling, and other control experiments suggest a radical-based mechanism. The fact that the reaction is carried out at ambient conditions, uses ubiquitous and inexpensive reagents, boasts a wide scope, and can be made highly atom economic, makes this new methodology a very appealing option for this archetypical organic reaction.
Isotope effects in nucleophilic substitution reactions. V. The mechanism of the decomposition of 1-phenylethyldimethylphenylammonium halides in chloroform
Joly, Helen Alma,Westaway, Kenneth Charles
, p. 1206 - 1214 (2007/10/02)
Secondary α and β hydrogen-deuterium kinetic isotope effects have been used together to show that the SN reaction between 1-phenylethyldimethylammonium ion and bromide or iodide in chloroform occurs by way of an SN2 mechanism within a triple ion in spite of the fact that it reacts faster than the primary substrate, benzyldimethylphenylammonium bromide.The very loose transition state and steric effects in the ground state appear to be responsible for the unusually fast SN2 reactions between 1-phenylethyldimethylphenylammonium ion and halide ions in chloroform.
