23111-43-5Relevant articles and documents
Ag-Cu copromoted direct C2-H bond thiolation of azoles with Bunte salts as sulfur sources
Du, Xiao,Hu, Yuntao,Wang, Rui,Wei, Yingsu,Xu, Hongyan,Zhang, Ying,Zhao, Huaiqing
supporting information, p. 5899 - 5904 (2021/07/12)
A direct C2-H thiolation of azoles with Bunte salts was achieved under the combined action of copper and silver salts. This protocol could furnish various substituted 2-thioazoles in moderate to good yields. This method has a broad substrate scope and shows good functional group tolerance.
Structure-activity relationships of 2-benzylsulfanylbenzothiazoles: Synthesis and selective antimycobacterial properties
Klimesova, Vera,Koi, Jan,Palat, Karel,Stolarikova, Jirina,Dahse, Hans-Martin,Moellmann, Ute
experimental part, p. 281 - 292 (2012/09/08)
A set of 2-benzylsulfanyl derivatives of benzothiazole was synthesized and evaluated for antimicrobial and cytotoxic activities. The biological screening on antimicrobial activity against a panel of Gram-positive and Gramnegative bacteria, yeasts and fung
Novel aromatic fluoroolefins via fluoro-Julia-Kocienski olefination
Allendoerfer, Nadine,Es-Sayed, Mazen,Nieger, Martin,Braese, Stefan
experimental part, p. 3439 - 3448 (2010/12/19)
Fluoroolefins, which play an increasingly important role as peptide mimics in pharmaceuticals and as crop protection agents, are generated using a fluoro-Julia-Kocienski olefination. Their preparation can easily be accomplished using a Mitsunobu reaction and subsequent oxidation to generate the required benzothiazolyl sulfones. The key step of this process was the electrophilic -fluorination of the sulfone with N-fluorobenzenesulfonimide. The last stage of the successful synthesis of the fluoroolefins was the modified Julia-Kocienski olefination under basic conditions. Further functionalization was followed with the application of a Suzuki reaction. Georg Thieme Verlag Stuttgart.