231287-29-9

Basic information

• Product Name: 4-(3,5-dimethoxy-benzenesulfonyl)-aniline
• CAS NO: 231287-29-9
• Molecular Weight: 293.343
• Mol File: 231287-29-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3,5-dimethoxy-benzenesulfonyl)-aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3,5-dimethoxy-benzenesulfonyl)-aniline(231287-29-9)
• EPA Substance Registry System: 4-(3,5-dimethoxy-benzenesulfonyl)-aniline(231287-29-9)

Safety Data

• Hazardous Substances Data: 231287-29-9(Hazardous Substances Data)

Upstream product

• 231287-69-7 1,3-dimethoxy-5-(4-nitro-benzenesulfonyl)-benzene 
• 7439-89-6 iron 
• 100-00-5 4-chlorobenzonitrile 
• 231287-67-5 (3,5-dimethoxyphenyl)(4-nitrophenyl)sulfide 
• 19689-66-8 3,5-dimethoxybenzenethiol 

Relevant articles and documents

BENZOSULFONE DERIVATIVES

The present invention relates to novel compounds of the general formula STR1 wherein R 1 is hydrogen;R. sup.2 is hydrogen, trifluoromethyl or lower alkyl;R 3 is hydrogen or amino; or R 1 and R 2 or R 3 and R 2 taken together are--CH. dbd.CH--CH=CH--;Z is pyrimidin-4-yl, pyridin-4-yl, pyridin-2-yl or phenyl; R 4, R 5 are each independently hydrogen, lower alkyl, trifluoromethyl, halogen, lower alkoxy, nitrilo, amino, lower alkyl-amino, di-lower alkyl-amino, piperazinyl, morpholinyl, pyrrolidinyl, vinyl, C. sub.3-C 6 cycloalkyl, C 3-C 6 cycloalkenyl, t-buthylethinyl, hydroxyalkylethinyl, phenylethinyl, naphthyl, thiophenyl, or phenyl, which may be substituted by halogen, lower alkoxy, lower alkyl, trifluoromethyl or nitro, or a group--NH(CH. sub.2). sub.n NR 6 R 7,--N(CH 3)(CH 2) n NR 6 R. sup.7,--NH(CH 2) n-morpholin-4-yl or--NH(CH 2) n OH; n is 2-4R 6 and R 7 are each independently hydrogen or lower alkyl,and to their pharmaceutically acceptable salts. It has been found that the compounds of formula I possess a selective affinity to 5HT-6 receptors.