231299-15-3

Basic information

• Product Name: tert-butyl-[2-(4-methoxy-benzyloxy)-10-(tetrahydro-pyran-2-yloxy)-decyloxy]-diphenyl-silane
• CAS NO: 231299-15-3
• Molecular Weight: 632.956
• Mol File: 231299-15-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl-[2-(4-methoxy-benzyloxy)-10-(tetrahydro-pyran-2-yloxy)-decyloxy]-diphenyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl-[2-(4-methoxy-benzyloxy)-10-(tetrahydro-pyran-2-yloxy)-decyloxy]-diphenyl-silane(231299-15-3)
• EPA Substance Registry System: tert-butyl-[2-(4-methoxy-benzyloxy)-10-(tetrahydro-pyran-2-yloxy)-decyloxy]-diphenyl-silane(231299-15-3)

Safety Data

• Hazardous Substances Data: 231299-15-3(Hazardous Substances Data)

Upstream product

• 53963-10-3 2-[(6-bromohexyl)oxy]tetrahydro-2H-pyran 
• 221677-67-4 (-)-(S)-4-(tert-butyldiphenylsilyloxy)-3-(4-methoxybenzyloxy)butyl 4-methylbenzenesulfonate 
• 231299-11-9 (2S,4S)-tert-butyl-[2-(4-methoxy-phenyl)-[1,3]dioxan-4-ylmethoxy]-diphenyl-silane 
• 103708-37-8 (2S,4S)-4-hydroxymethyl-2-(p-methoxymethyl)-1,3-dioxane 
• 117021-10-0 1-[(tetrahydro-2H-pyran-2-yl)oxy]-6-hexylmagnesium bromide 

Downstream Products

• 221677-66-3 cepaciamide B p-methoxybenzyl ether 
• 221677-54-9 (S)-2-(p-methoxybenzyloxy)-11-octadecyn-1-ol 
• 221677-62-9 (2S,11Z)-2-(p-methoxybenzyloxy)-11-octadecenoic acid 
• 221677-63-0 (2S,11Z)-2-(p-methoxybenzyloxy)-11-octadecen-1-ol 
• 231299-16-4 (S)-10-(tert-butyldiphenylsilyloxy)-9-(p-methoxybenzyloxy)-1-decanol 
• 221677-53-8 (S)-10-(tert-butyldiphenylsilyloxy)-9-(p-methoxybenzyloxy)-1-decyl bromide 

Relevant articles and documents

Total syntheses of cepaciamides A and B, novel fungitoxic 3-amino-2- piperidinone-containing lipids produced by Pseudomonas cepacia D-202

Total syntheses of cepaciamides A and B were accomplished. (R)-3-Amino- 2-piperidinone was obtained via cyclization of (R)-ornithine. The common amide-linked fatty acid was synthesized via Sharpless AD as the key step. Amide-formation was achieved with DEPC. In the preparation of two fatty acid segments, (S)-malic acid was used as the chiral source to introduce (2S)- configuration. A known chiral cyclopropane derivative was introduced in the segment of cepaciamide A. The formation of (Z)-olefin in the segment of cepaciamide B was achieved by means of partial reduction of the acetylenic bond. Esterification between the fatty acid-segments and the amide-segment with DCC/DMAP and subsequent oxidative deprotection of the MPM group with CAN gave cepaciamides.