23152-51-4

Basic information

• Product Name: C₉H₁₀F₃N₃O
• CAS NO: 23152-51-4
• Molecular Weight: 233.193
• Mol File: 23152-51-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₉H₁₀F₃N₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₉H₁₀F₃N₃O(23152-51-4)
• EPA Substance Registry System: C₉H₁₀F₃N₃O(23152-51-4)

Safety Data

• Hazardous Substances Data: 23152-51-4(Hazardous Substances Data)

Upstream product

• 624-83-9 methyl isocyanate 
• 368-78-5 3-(trifluoromethyl)phenylhydrazine 

Relevant articles and documents

Anticonvulsant 4-Aryl Semicarbazides and Thioureas

Among a series of anticonvulsant 1-aryl semicarbazides, 1-(3,5-bistrifluoromethyl)phenylsemicarbazide, C 3884-Go (11) and its 4-methyl derivative, C 3165-Go (12) showed good activity of long duration in the electroshock test in mice and rats.Quantitative structure activity analysis indicates that ? and ? values are respectively important for the aromatic and side chain substituents respectively.N-Acetyl-N'-(3,5-bistrifluoromethyl)phenyl hydrazine (20) is highly anticonvulsant but causes ataxia. 4-Aryl thiosemicarbazides show weak to moderate activity.Among N-(3,5-bistrifluoromethyl)phenyl thiocarbamoyl derivatives, the product 33 from N-benzyl piperazine is potent in the electroshock test.Compounds 11 and 12 have been compared with standards such as phenytoin, phenurone and carbamazepine.