23159-73-1 Usage
General Description
1-(4-hydroxyphenyl)-3-propan-2-ylurea, also known as hydroxy acetophenone, is a chemical compound with the molecular formula C11H13NO2. It is a derivative of phenylurea and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1-(4-hydroxyphenyl)-3-propan-2-ylurea has a white crystalline solid appearance and is soluble in organic solvents. It has various applications in the pharmaceutical and agricultural industries due to its ability to act as an antimicrobial, antifungal, and anti-inflammatory agent. Additionally, it has potential uses in the cosmetic and personal care industries.
Check Digit Verification of cas no
The CAS Registry Mumber 23159-73-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,5 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 23159-73:
(7*2)+(6*3)+(5*1)+(4*5)+(3*9)+(2*7)+(1*3)=101
101 % 10 = 1
So 23159-73-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O2/c1-7(2)11-10(14)12-8-3-5-9(13)6-4-8/h3-7,13H,1-2H3,(H2,11,12,14)
23159-73-1Relevant articles and documents
Synthesis and SAR studies of potent H+/K+-ATPase and anti-inflammatory activities of symmetrical and unsymmetrical urea analogues
Rakesh, Kadalipura P.,Darshini, Nanjudappa,Vidhya, Sunnadadoddi L.,Rajesha,Mallesha, Ningegowda
, p. 1675 - 1681 (2017/06/27)
A sequence of symmetrical and unsymmetrical urea derivatives 1–24 were synthesized and characterized by standard spectroscopic techniques. The synthesized analogues were tested for their in vitro H+/K+-ATPase and anti-inflammatory activities. The majority of the compounds showed outstanding activity, compared to that of omeprazole and indomethacin, usual standard drugs of antiulcer and anti-inflammatory, respectively. In particular, hydroxy, methyl, and methoxy derivatives 13–24 were the most active compounds possessing a significant amplify for diverse substituents on the benzene ring thus, contributing positively to gastric ulcer inhibition. Compounds 1–3 and 22–24 showed excellent anti-inflammatory activity due to the presence of electron-withdrawing groups (Cl and F) on the molecule.
