231622-37-0

Basic information

• Product Name: 1-benzyl-3-(4-chloro-phenyl)-pyrrolidine
• CAS NO: 231622-37-0
• Molecular Weight: 271.79
• Mol File: 231622-37-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-3-(4-chloro-phenyl)-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3-(4-chloro-phenyl)-pyrrolidine(231622-37-0)
• EPA Substance Registry System: 1-benzyl-3-(4-chloro-phenyl)-pyrrolidine(231622-37-0)

Safety Data

• Hazardous Substances Data: 231622-37-0(Hazardous Substances Data)

Upstream product

• 14774-78-8 4-chlorophenyl lithium 
• 104016-82-2 (3R)-1-benzyl-3-methanesulfonyloxy pyrrolidine 

Downstream Products

• 120418-62-4 3-(4-chlorophenyl)pyrrolidine 

Relevant articles and documents

N-Substituted-3-arylpyrrolidines: Potent and Selective Ligands at Serotonin 1A Receptor

3-Arylpyrrolidines are synthesized through the coupling of N-benzyl-3-(methanesulfonyloxy)pyrrolidine with diarylcuprates. Pharmacological evaluation of a series of N-substituted-3-arylpyrrolidines toward several neurotransmitter receptors indicated that some of them are good ligands for serotonin 1A receptor. Particularly, N-pyrrolidines were found to be potent and selective ligands. A preliminary biological evaluation for several selected compounds indicated that they are potentially effective antianxiety and antidepressant agents.