23167-99-9

Basic information

• Product Name: 2,4-dipropylphenol
• Synonyms: 2,4-dipropylphenol
• CAS NO: 23167-99-9
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 0
• Mol File: 23167-99-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 270.52°C (rough estimate)
• Appearance: /
• Density: 0.9249 (rough estimate)
• Refractive Index: 1.5091 (estimate)
• Water Solubility: 25mg/L(25 oC)
• CAS DataBase Reference: 2,4-dipropylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dipropylphenol(23167-99-9)
• EPA Substance Registry System: 2,4-dipropylphenol(23167-99-9)

Safety Data

• Hazardous Substances Data: 23167-99-9(Hazardous Substances Data)

Usage

General Description

2,4-dipropylphenol, also known as propofol, is a chemical compound that is commonly used as a general anesthetic. It is a clear, colorless liquid that is administered intravenously to induce and maintain anesthesia during surgical procedures. Propofol is known for its rapid onset and short duration of action, making it a popular choice for anesthesia in both children and adults. It works by enhancing the activity of gamma-aminobutyric acid (GABA) receptors in the brain, resulting in sedation and unconsciousness. However, propofol also has potential side effects, including respiratory depression, hypotension, and the risk of addiction or abuse. Overall, 2,4-dipropylphenol is a key compound in modern anesthesia and plays a crucial role in medical procedures requiring sedation and unconsciousness.

Upstream product

• 92156-96-2 2-Hydroxy-3,5-dipropyl-benzoesaeure 
• 121-69-7 N,N-dimethyl-aniline 
• 71-23-8 propan-1-ol 
• 645-56-7 4-n-Propylphenol 
• 622-85-5 propoxybenzene 
• 644-35-9 5-propylphenol 
• 194792-41-1 1-(4-hydroxy-3-propyl-phenyl)-propan-1-one 
• 215586-02-0 propionic acid-(2-propyl-phenyl ester) 
• 860756-99-6 3,5-diallyl-2-hydroxy-benzoic acid 

Downstream Products

• 215585-98-1 6-bromo-2,4-dipropylphenol 
• 215586-00-8 5,7-dipropyl-2-(4'-hydroxy-3'-methoxyphenyl)benzo[b]furan 
• 215585-99-2 5,7-dipropyl-2-(4'-benzyloxy-3'-methoxyphenyl)benzo[b]furan 
• 51571-14-3 2-Aminomethyl-4,6-dipropyl-phenol; hydrochloride 
• 92729-83-4 1-(2-hydroxy-3,5-dipropyl-phenyl)-propan-1-one 

Relevant articles and documents

XH-14 analogues as adenosine antagonists

Analogues of the potent adenosine antagonist 5-(3'-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzo[b]furan-3-carbaldehyde (XH-14, 1) with alternate substituents in the 2-, 5- and 7-positions have been synthesised. The affinity of these compo

Alumina-Catalyzed Reactions of Hydroxyarenes and Hydroaromatic Ketones. 9. Reaction of Phenol with 1-Propanol

At 250-350 deg C in the presence of alumina, phenol (1) reacts with excess 1-propanol to give mainly (>90percent) C-alkylation to form mono- to penta-n-propylphenols plus some O-alkylations to form n-propyl aryl ethers. The principal component of the product mixture from 1 is 2,6-di-n-propylphenol (26-50 mol percent yield). With 4-n-propylphenol as substrate (instead of 1), tri-, tetra-, and penta-n-propylphenols are formed in 48-79percent combined yield. On the average, only 3percent of the total C3H7 groups in the product mixture are isopropyl ones. Deoxygenation is not observed. It is proposed that the principal products result from an SN2-type reaction mechanism which involves nucleophilic attack (variously by C-2, C-4, C-6, or O) of an adsorbed ambident phenoxide ion onto C-1 of an adsorbed n-propoxide group. n-Propylation at C-3 and C-5 of the phenol ring results from surface-catalyzed dienone-phenol rearrangement.Isopropylation may occur via a side reaction of SN1 type.