23181-80-8

Basic information

• Product Name: 7-aminoheptanenitrile
• Synonyms: 7-aminoheptanenitrile
• CAS NO: 23181-80-8
• Molecular Formula: C₇H₁₄N₂
• Molecular Weight: 126.23
• Mol File: 23181-80-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 242.8°C at 760 mmHg
• Flash Point: 100.6°C
• Appearance: /
• Density: 0.894g/cm³
• Vapor Pressure: 0.0333mmHg at 25°C
• Refractive Index: 1.449
• CAS DataBase Reference: 7-aminoheptanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 7-aminoheptanenitrile(23181-80-8)
• EPA Substance Registry System: 7-aminoheptanenitrile(23181-80-8)

Safety Data

• Hazardous Substances Data: 23181-80-8(Hazardous Substances Data)

Usage

Hazard

Moderately toxic by ingestion.

InChI:InChI=1/C7H14N2/c8-6-4-2-1-3-5-7-9/h1-6,8H2

Upstream product

• 646-20-8 pimelonitrile 
• 101112-56-5 N-(6-cyano-hexyl)-phthalimide 
• 22819-91-6 7-chloroheptanenitrile 
• 20965-27-9 7-bromo-heptanonitrile 
• 58793-92-3 7-azidoheptanenitrile 
• 17976-80-6 7-hydroxyheptanenitrile 

Downstream Products

• 101260-22-4 N,N'-bis-(6-cyano-hexyl)-thiourea 
• 929-17-9 7-aminoheptanoic acid 
• 62578-20-5 N-(6-Cyano-hexyl)-4-trifluoromethoxy-benzamide 
• 62578-15-8 N¹-Propyl-heptane-1,7-diamine 
• 13069-37-9 7-[2-(2-Methoxy-phenoxy)-ethylamino]-heptanenitrile 
• 98490-17-6 7-isothiocyanato-heptanenitrile 
• 98553-64-1 (6-cyano-hexyl)-thiourea 
• 100952-18-9 N-benzyl-N'-(6-cyano-hexyl)-thiourea 
• 62578-25-0 2-(7-amino-heptylamino)-ethanol 
• 62578-14-7 C₂₆H₃₀F₆N₂O₄ 
• 1032916-09-8 N,N'-(bisheptanenitrile) oxalamide 
• 1231718-21-0 7-(((11RS)-3-chloro-6-methyl-6,11-dihydro-dibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanenitrile S,S-dioxide 

Relevant articles and documents

Amination of ω-Functionalized Aliphatic Primary Alcohols by a Biocatalytic Oxidation-Transamination Cascade

Amination of non-activated aliphatic fatty alcohols to the corresponding primary amines was achieved through a five-enzyme cascade reaction by coupling a long-chain alcohol oxidase from Aspergillus fumigatus (LCAO-Af) with a ω-transaminase from Chromobacterium violaceum (ω-TA-Cv). The alcohol was oxidized at the expense of molecular oxygen to yield the corresponding aldehyde, which was subsequently aminated by the PLP-dependent ω-TA to yield the final primary amine product. The overall cascade was optimized with respect to pH, O2 pressure, substrate concentration, decomposition of H2O2 (derived from alcohol oxidation), NADH regeneration, and biocatalyst ratio. The substrate scope of this concept was investigated under optimized conditions by using terminally functionalized C4-C11 fatty primary alcohols bearing halogen, alkyne, amino, hydroxy, thiol, and nitrile groups.