23181-87-5

Basic information

• Product Name: meso-N,N'-Bis-(carbobenzoxy)-α,α'-diamino-bernsteinsaeure
• Synonyms: meso-N,N'-Bis-(carbobenzoxy)-α,α'-diamino-bernsteinsaeure
• CAS NO: 23181-87-5
• Molecular Weight: 416.387
• Mol File: 23181-87-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: meso-N,N'-Bis-(carbobenzoxy)-α,α'-diamino-bernsteinsaeure(CAS DataBase Reference)
• NIST Chemistry Reference: meso-N,N'-Bis-(carbobenzoxy)-α,α'-diamino-bernsteinsaeure(23181-87-5)
• EPA Substance Registry System: meso-N,N'-Bis-(carbobenzoxy)-α,α'-diamino-bernsteinsaeure(23181-87-5)

Safety Data

• Hazardous Substances Data: 23181-87-5(Hazardous Substances Data)

Upstream product

• 921-52-8 2,3-Diaminosuccinic acid 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 38484-76-3 dibenzyl ((3S,4S)-2,5-dioxotetrahydrofuran-3,4-diyl)dicarbamate 

Relevant articles and documents

CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES

A novel cross-linked cytotoxic agents, pyrrolobenzo-diazepine dimer (PBD) derivatives, and their conjugates to a cell-binding molecule, a method for preparation of the conjugates and the therapeutic use of the conjugates.

CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE

What provided is the conjugation of cytotoxic to a cell-binding molecule with a bis-linker(dual-linker) as shown in Formula (I). It provides bis-linkage methods of making a conjugate of a cytotoxic drug molecule to a cell-binding agent in a specific manner. It also relates to application of the conjugates for the treatment of a cancer, or an autoimmune disease, or an infectious disease.