23194-66-3 Usage
General Description
"(3-Methoxy-phenyl)-oxo-acetonitrile" is a chemical compound with the molecular formula C9H7NO2. (3-METHOXY-PHENYL)-OXO-ACETONITRILE is a nitrile derivative with a phenyl group substituted with a methoxy group and a carbonyl group attached to a nitrile functional group. It is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals, agrochemicals, and other fine chemicals. The presence of the nitrile functional group makes this compound a versatile intermediate for the synthesis of a wide range of compounds with diverse chemical and biological properties. Additionally, the presence of the methoxy group can lead to altered chemical and biological activities in compounds derived from this precursor.
Check Digit Verification of cas no
The CAS Registry Mumber 23194-66-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,9 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 23194-66:
(7*2)+(6*3)+(5*1)+(4*9)+(3*4)+(2*6)+(1*6)=103
103 % 10 = 3
So 23194-66-3 is a valid CAS Registry Number.
23194-66-3Relevant articles and documents
A Cyanide-Free Synthesis of Acylcyanides through Ru-Catalyzed C(sp3)-H-Oxidation of Benzylic Nitriles
Eisele, Pascal,Bauder, Michael,Hsu, Shih-Fan,Plietker, Bernd
, p. 689 - 691 (2019/05/07)
A practical method for generation of acylcyanides devoid of any external cyanide sources is presented that relies on a mild Ru-catalyzed selective C?H-oxidation of benzylic nitriles. The starting materials are smoothly generated through condensation of the corresponding carboxylic acid amides using silanes. The obtained acylcyanides can be employed in a plethora of transformation as exemplified to some larger extend in the sequence of C?H-oxidation-Tischenko-rearrangement for the generation of structurally diverse benzoyloxycyanohydrines.
A new convenient synthesis of aroyl cyanides via the formation of cyanohydrin nitrate intermediates
Sueda, Takuya,Shoji, Masashi,Nishide, Kiyoharu
, p. 5070 - 5072 (2008/12/21)
The treatment of α-bromoarylacetonitriles with AgNO3 generates cyanohydrin nitrate intermediates, which easily eliminate nitrous acid with the formation of carbonyl bond to afford aroyl cyanides in good to high yields.
