23225-02-7

Basic information

• Product Name: 4(3H)-Quinazolinone, 2,2'-dithiobis[3-(4-methoxyphenyl)-
• CAS NO: 23225-02-7
• Molecular Formula: C30H22N4O4S2
• Molecular Weight: 566.661
• Mol File: 23225-02-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4(3H)-Quinazolinone, 2,2'-dithiobis[3-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(3H)-Quinazolinone, 2,2'-dithiobis[3-(4-methoxyphenyl)-(23225-02-7)
• EPA Substance Registry System: 4(3H)-Quinazolinone, 2,2'-dithiobis[3-(4-methoxyphenyl)-(23225-02-7)

Safety Data

• Hazardous Substances Data: 23225-02-7(Hazardous Substances Data)

Upstream product

• 1031-88-5 3‐(4‐methoxyphenyl)‐2‐thioxo‐2,3‐dihydroquinazolin‐4(1H)‐one 

Relevant articles and documents

Synthesis, properties, and mass-spectrometric fragmentation of 2-thio derivatives of 3-arylquinazolin-4-ones

We have studied the reactions of alkylation, oxidation, and hydrolysis of 3-aryl-2-thioxoquinazolin-4-ones. Alkylation in an alkaline medium occurs exclusively at the sulfur atom. Oxidation by hydrogen peroxide leads to formation of 3-arylquinazoline-2,4-diones. The latter are also obtained in base or acid hydrolysis of the synthesized S-alkyl derivatives. When 3-aryl-2-thioxoquinazolin-4-ones are reacted with iodine, we obtain the disulfides, while the reaction with chlorine in hydrochloric acid leads to 2-chloroquinazolin-4-ones. Studying the mass spectrometric behavior of the compounds obtained made it possible to observe in the gas phase ring-chain isomerization of the heterocyclic ring, and also S-N migration of the propargyl radical in molecular ions of the S-propargyl derivatives.