232275-73-9

Basic information

• Product Name: N-BOC-4-AMINO-2-CHLOROBENZOIC ACID
• Synonyms: N-BOC-4-AMINO-2-CHLOROBENZOIC ACID;BOC-4-AMINO-2-CHLOROBENZOIC ACID;4-(Boc-aMino)-2-chlorobenzoic acid, 97%;2-Chloro-4-(Boc-aMino)-benzoic acid;Benzoic acid,2-chloro-4-[[(1,1-dimethylethoxy)carbonyl]amino]-
• CAS NO: 232275-73-9
• Molecular Formula: C₁₂H₁₄ClNO₄
• Molecular Weight: 271.7
• Mol File: 232275-73-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 353.0±32.0 °C(Predicted)
• Appearance: /
• Density: 1.338±0.06 g/cm3(Predicted)
• PKA: 3.14±0.25(Predicted)
• CAS DataBase Reference: N-BOC-4-AMINO-2-CHLOROBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-BOC-4-AMINO-2-CHLOROBENZOIC ACID(232275-73-9)
• EPA Substance Registry System: N-BOC-4-AMINO-2-CHLOROBENZOIC ACID(232275-73-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 232275-73-9(Hazardous Substances Data)

Usage

General Description

N-BOC-4-AMINO-2-CHLOROBENZOIC ACID is a chemical compound used in the synthesis of pharmaceuticals and agrochemicals. It is a derivative of 4-aminobenzoic acid and contains a BOC (tert-butoxycarbonyl) protecting group on the amino group. The compound is commonly used as an intermediate in the preparation of various bioactive molecules and is also employed in the development of new drugs and chemical entities. Its specific properties and reactivity make it an important building block in organic synthesis, particularly in the field of medicinal and agricultural chemistry.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 2457-76-3 4-amino-2-chlorobenzoic acid 

Downstream Products

• 232275-74-0 2-chloro-4-[N-methyl-N-(tert-butoxycarbonyl)amino]benzoic acid methyl ester 
• 204972-82-7 2-chloro-4-(methylamino)benzoic acid methyl ester 
• 937040-25-0 (2-chloro-4-methylamino-phenyl)-methanol 

Relevant articles and documents

Inhibitors of α4 mediated cell adhesion

The present invention relates to a pharmaceutical composition comprising as an active ingredient a compound of formula (I), wherein Ring A is an aromatic or a heterocyclic ring; Q is a bond, carbonyl, lower alkylene, lower alkenylene, —O-(lower alkylene)-, etc.; n is 0, 1 or 2; Z is oxygen or sulfur, W is oxygen, sulfur, —CH═CH—, —NH— or —N═CH—; R1, R2and R3are the same or different and are hydrogen, halogen, hydroxyl, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted lower alkoxy group, a substituted or unsubstituted amino group, etc.; R4is tetrazolyl, carboxyl group, amide or ester; R5is hydrogen, nitro, amino, hydroxyl, lower alkanoyl, lower alkyl etc.; R6is selected from (a) a substituted or unsubstituted phenyl group, (b) a substituted or unsubstituted pyridyl group, (c) a substituted or unsubstituted thienyl group, (d) a substituted or unsubstituted benzofuranyl group, etc.; or a pharmaceutically acceptable salt thereof.