23255-41-6 Usage
General Description
S-[2-(acetylamino)ethyl] 3-oxobutanethioate is a chemical compound with the molecular formula C8H13NO3S. It is also known by the systematic name N-acetyl-S-(2-oxo-3-butenyl)-l-cysteine and is a derivative of the amino acid cysteine. S-[2-(acetylamino)ethyl] 3-oxobutanethioate is often used in the synthesis of peptides and in biochemical research as a reagent for the detection of sulfhydryl groups in proteins. It is also known to have anti-inflammatory properties and has been studied for its potential pharmacological uses in the treatment of conditions such as arthritis and inflammatory bowel disease. Additionally, it is used in the production of cosmetic and personal care products due to its ability to regulate skin hydration and protect against UV-induced damage. Overall, S-[2-(acetylamino)ethyl] 3-oxobutanethioate is a versatile compound with various applications in medicine, biochemistry, and the cosmetic industry.
Check Digit Verification of cas no
The CAS Registry Mumber 23255-41-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,2,5 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 23255-41:
(7*2)+(6*3)+(5*2)+(4*5)+(3*5)+(2*4)+(1*1)=86
86 % 10 = 6
So 23255-41-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H13NO3S/c1-6(10)5-8(12)13-4-3-9-7(2)11/h3-5H2,1-2H3,(H,9,11)
23255-41-6Relevant articles and documents
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Sheehan,Beck
, p. 4875 (1955)
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Employing modular polyketide synthase ketoreductases as biocatalysts in the preparative chemoenzymatic syntheses of diketide chiral building blocks
Piasecki, Shawn K.,Taylor, Clint A.,Detelich, Joshua F.,Liu, June,Zheng, Jianting,Komsoukaniants, Arkady,Siegel, Dionicio R.,Keatinge-Clay, Adrian T.
experimental part, p. 1331 - 1340 (2012/02/01)
Chiral building blocks are valuable intermediates in the syntheses of natural products and pharmaceuticals. A scalable chemoenzymatic route to chiral diketides has been developed that includes the general synthesis of α-substituted, β-ketoacyl N-acetylcysteamine thioesters followed by a biocatalytic cycle in which a glucose-fueled NADPH-regeneration system drives reductions catalyzed by isolated modular polyketide synthase (PKS) ketoreductases (KRs). To identify KRs that operate as active, stereospecific biocatalysts, 11 isolated KRs were incubated with 5 diketides and their products were analyzed by chiral chromatography. KRs that naturally reduce small polyketide intermediates were the most active and stereospecific toward the panel of diketides. Several biocatalytic reactions were scaled up to yield more than 100 mg of product. These syntheses demonstrate the ability of PKS enzymes to economically and greenly generate diverse chiral building blocks on a preparative scale.
