232617-93-5Relevant articles and documents
Phenylalanine derivatives
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, (2008/06/13)
Phenylalanine derivatives of formula (1) are described: wherein R is a carboxylic acid or a derivative thereof; L1is a linker atom or group; Het is an optionally substituted heteroaromatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the binding of alpha4 integrins to their ligands and are of use in the prophylaxis and treatment of immune or inflammatory disorders.