2328091-01-4

Basic information

• Product Name: C₁₁H₁₃BrN₄O₂
• CAS NO: 2328091-01-4
• Molecular Weight: 313.154
• Mol File: 2328091-01-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₃BrN₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₃BrN₄O₂(2328091-01-4)
• EPA Substance Registry System: C₁₁H₁₃BrN₄O₂(2328091-01-4)

Safety Data

• Hazardous Substances Data: 2328091-01-4(Hazardous Substances Data)

Upstream product

• 937046-98-5 7-bromo-pyrrolo[2,1-f][1,2,4]triazin-4-ylamine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 158227-80-6 7-((2S,3S,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)-tetrahydrofuran-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine 
• 1191237-69-0 (2R,3R,4S,5R)?2?(4?aminopyrrolo[1,2?f][1,2,4]triazin?7?yl)?3,4?dihydroxy?5?(hydroxymethyl)tetrahydrofuran?2?carbonitrile 
• 1911578-75-0 (2S)-2-ethylbutyl 2-(((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 

Relevant articles and documents

Preparation method of Remdesivir

The invention relates to a preparation method of Remdesivir. 4-amino-7-bromopyrrolo [2, 1-f][1, 2, 4] triazine and (3alpha R, 6R, 6alpha R)-6-(benzyloxymethyl)-2, 2-dimethyl dihydrofuran [3, 4-d] [1,3] dioxo-4 (4alpha H)-one are taken as a raw material, amino protection reaction, coupling reaction, substitution reaction, debenzylation reaction, resolution, alcoholysis reaction, amidation reaction, deprotection reaction and resolution nine reaction steps are carried out so as to synthesize Remdesivir at a high yield. The preparation method of Remdesivir provided by the invention is a preparation method which is high in yield, low in cost, easy to operate and suitable for industrialization.

5'-Deoxidation-5'-isopropyl-substituted-amino nucleoside compound and preparing method and application thereof

The invention discloses a 5'-deoxidation-5'-isopropyl-substituted-amino nucleoside compound shown in a formula 7, a preparing method of the compound shown in the formula 7 and application of the compound shown in the formula 7 to preparing a 5'-deoxidation-5'-polysubstitution amino nucleoside compound 1 as a midbody. The formula is defined in the description.