23285-07-6

Basic information

• Product Name: 4(3H)-Quinazolinone, 2,2'-dithiobis[3-phenyl-
• CAS NO: 23285-07-6
• Molecular Formula: C28H18N4O2S2
• Molecular Weight: 506.609
• Mol File: 23285-07-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4(3H)-Quinazolinone, 2,2'-dithiobis[3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(3H)-Quinazolinone, 2,2'-dithiobis[3-phenyl-(23285-07-6)
• EPA Substance Registry System: 4(3H)-Quinazolinone, 2,2'-dithiobis[3-phenyl-(23285-07-6)

Safety Data

• Hazardous Substances Data: 23285-07-6(Hazardous Substances Data)

Upstream product

• 18741-24-7 3-phenyl-2-thioxo-2,3-dihydro-1H-quinazolin-4-one 
• 18741-24-7 2-mercapto-3-phenyl-3H-quinazolin-4-one 
• 103-72-0 phenyl isothiocyanate 
• 118-92-3 anthranilic acid 

Relevant articles and documents

Synthesis, properties, and mass-spectrometric fragmentation of 2-thio derivatives of 3-arylquinazolin-4-ones

We have studied the reactions of alkylation, oxidation, and hydrolysis of 3-aryl-2-thioxoquinazolin-4-ones. Alkylation in an alkaline medium occurs exclusively at the sulfur atom. Oxidation by hydrogen peroxide leads to formation of 3-arylquinazoline-2,4-diones. The latter are also obtained in base or acid hydrolysis of the synthesized S-alkyl derivatives. When 3-aryl-2-thioxoquinazolin-4-ones are reacted with iodine, we obtain the disulfides, while the reaction with chlorine in hydrochloric acid leads to 2-chloroquinazolin-4-ones. Studying the mass spectrometric behavior of the compounds obtained made it possible to observe in the gas phase ring-chain isomerization of the heterocyclic ring, and also S-N migration of the propargyl radical in molecular ions of the S-propargyl derivatives.

N-HALOSUCCINIMIDE/SULFURIC ACID: AN EFFICIENT REAGENT FOR THE SYNTHESIS OF FUSED BENZOTHIAZOLES

A new version of Hugershoff's synthesis is reported.The cyclizing agent, N-halosuccinimide/sulfuric acid permits the preparation of complex fused benzothiazoles in very good yields.