233279-11-3

Basic information

• Product Name: (E)-2-(Hydroxyimino)-3-(1-pyrrolidinyl)-N-phenylpropanamid
• CAS NO: 233279-11-3
• Molecular Weight: 247.297
• Mol File: 233279-11-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2-(Hydroxyimino)-3-(1-pyrrolidinyl)-N-phenylpropanamid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(Hydroxyimino)-3-(1-pyrrolidinyl)-N-phenylpropanamid(233279-11-3)
• EPA Substance Registry System: (E)-2-(Hydroxyimino)-3-(1-pyrrolidinyl)-N-phenylpropanamid(233279-11-3)

Safety Data

• Hazardous Substances Data: 233279-11-3(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 50-00-0 formaldehyd 
• 42366-35-8 (E)-2-(Hydroxyimino)-N-phenylacetamid 
• 7309-47-9 bis(N-pyrrolidinyl)methane 

Relevant articles and documents

α-dicarbonylmonoximes as nucleophiles and neighbour groups

The α-dicarbonylmonooximes 1 and 11 do not react as simple "CH-acidic-compounds" in the Mannich condensation. In a concerted reaction with aminals in absolute dioxane they give rise to the products 4a - e and 12a - e with better practicability and much higher yields compared with the conventional method. The Mannich bases with a cyclic amine part show in the dehydrogenation, using mercury-EDTA, a neighbouring group participation of the oxime in type 4 and of the oxime or amide function in 12 yielding cyclized products. For the reaction a plausible mechanism is proposed.