23328-60-1

Basic information

• Product Name: 2-[2-(2-hydroxyethoxy)ethoxy]ethyl laurate
• Synonyms: 2-[2-(2-hydroxyethoxy)ethoxy]ethyl laurate;Dodecanoic acid 2-[2-(2-hydroxyethoxy)ethoxy]ethyl ester;Einecs 245-586-0
• CAS NO: 23328-60-1
• Molecular Formula: C₁₈H₃₆O₅
• Molecular Weight: 332.47544
• EINECS: 245-586-0
• Mol File: 23328-60-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 431°Cat760mmHg
• Flash Point: 139.7°C
• Appearance: /
• Density: 0.979g/cm³
• Vapor Pressure: 3.08E-09mmHg at 25°C
• Refractive Index: 1.455
• CAS DataBase Reference: 2-[2-(2-hydroxyethoxy)ethoxy]ethyl laurate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(2-hydroxyethoxy)ethoxy]ethyl laurate(23328-60-1)
• EPA Substance Registry System: 2-[2-(2-hydroxyethoxy)ethoxy]ethyl laurate(23328-60-1)

Safety Data

• Hazardous Substances Data: 23328-60-1(Hazardous Substances Data)

Usage

Chemical composition

Derived from lauric acid and ethylene glycol.

Common uses

用作乳化剂和表面活性剂，用于各种个人护理和化妆品。

Functionality

稳定油包水乳化液，改善乳霜和乳液的质地和一致性，增强化妆品配方的涂抹性和整体性能。

Safety

在低浓度下相对安全，但可能会导致某些敏感皮肤的人发炎或过敏。

InChI:InChI=1/C18H36O5/c1-2-3-4-5-6-7-8-9-10-11-18(20)23-17-16-22-15-14-21-13-12-19/h19H,2-17H2,1H3

Upstream product

• 143-07-7 lauric acid 
• 112-16-3 n-dodecanoyl chloride 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 

Relevant articles and documents

Highly Efficient Encapsulation and Phase Separation of Apolar Molecules by Magnetic Shell-by-Shell-Coated Nanocarriers in Water

We report on the development of a supramolecular nanocarrier concept that allows for the encapsulation and separation of small apolar molecules from water. The nanocarriers consist of shell-by-shell-coated nanoparticles such as TiO2 and ferromagnetic Fe3O4. The first ligand shell is provided by covalently bound hexadecyl phosphonic acid (PAC16) and the second shell by noncovalently assembled amphiphiles rendering the hybrid architecture soluble in water. Agitation of these constructs with water containing the hydrocarbons G1–G4, the fluorescent marker G5, the polychlorinated biphenyl PCB 77, or crude oil leads to a very efficient uptake (up to 411 %) of the apolar contaminant. In case of the hybrids containing a Fe3O4 core, straightforward phase separation by the action of an external magnet is provided. The load can easily be released by a final treatment with an organic solvent.

Manufacturing Nanoparticles with Orthogonally Adjustable Dispersibility in Hydrocarbons, Fluorocarbons, and Water

We describe a universal wet-chemical shell-by-shell coating procedure resulting in colloidal titanium dioxide (TiO2) and iron oxide (Fe3O4) nanoparticles with dynamically and reversibly tunable surface energies. A strong c

Combinatorial synthesis of PEG oligomer libraries

A simple chain-extending approach was established for the scale-up of the monoprotected monodisperse PEG diol materials. Reactions of THP-(OCH2CH2)n—OMs (n=4, 8, 12) with a large excess of commercially available H—(OCH2CH2)n—OH (n=1-4) under basic conditions led to THP-(OCH2CH2)n—OH (n=5-15). Similarly, Me-(OCH2CH2)n—OH (n=4-11, 13) were prepared from Me-(OCH2CH2)n—OMs (n=3, 7, 11). For the chain elongation steps, 40-80% yields were achieved through extraction purification. PEG oligomer libraries I and II were generated in 50-95% overall yields by alkylation or acylation of THP-(OCH2CH2)n—OH (n=1-15) followed by deprotection. Alkylation of Me-(OCH2CH2)n—OH (n=1-11, 13) with X—(CH2)m—CO2R (X=Br or OMs) and subsequent hydrolysis led to PEG oligomer library III in 30-60% overall yields. Combinatorial purification techniques were adapted to the larger-scale library synthesis. A total of 498 compounds, each with a weight of 2-5 g and a minimum purity of 90%, were synthesized.