23373-38-8

Basic information

• Product Name: o-Toluenesulfonic acid, methyl ester
• Synonyms: o-Toluenesulfonic acid, methyl ester;Benzenesulfonic acid, 2-methyl-, methyl ester;2-methyl-benzenesulfonic aci methyl ester;2-Methylbenzenesulfonic acid, methyl ester;AXCVRQKOVCRCIX-UHFFFAOYSA-N
• CAS NO: 23373-38-8
• Molecular Formula: C₈H₁₀O₃S
• Molecular Weight: 186.2282
• Mol File: 23373-38-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 289.2°Cat760mmHg
• Flash Point: 128.7°C
• Appearance: /
• Density: 1.21g/cm³
• CAS DataBase Reference: o-Toluenesulfonic acid, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: o-Toluenesulfonic acid, methyl ester(23373-38-8)
• EPA Substance Registry System: o-Toluenesulfonic acid, methyl ester(23373-38-8)

Safety Data

• Hazardous Substances Data: 23373-38-8(Hazardous Substances Data)

Upstream product

• 124-41-4 sodium methylate 
• 133-59-5 Toluene-2-sulfonyl chloride 
• 67-56-1 methanol 
• 2093-46-1 2-methylphenyl diazonium tetrafluoroborate 

Downstream Products

• 212322-35-5 1-Methyl-2-[N-(4-thiocarbamoyl-phenyl)aminomethyl]-indol-5-yl-carboxylic acid-N-phenyl-N-(2-methoxycarbonylethyl)-amide 
• 2654-52-6 2,3-dimethylbenzothiazolium toluene-4-sulfonate 

Relevant articles and documents

Copper-Catalyzed Multicomponent Reaction of DABCO·(SO2)2, Alcohols, and Aryl Diazoniums for the Synthesis of Sulfonic Esters

A Cu-catalyzed multicomponent cascade reaction of DABCO·(SO2)2 (DABSO), alcohol, and aryl diazonium tetrafluoroborate was developed which afforded sulfonic esters in moderate to good chemical yields. In this reaction, the SO2 surrogate DABSO was used for the first time in the synthesis of sulfonic aliphatic esters. This multicomponent reaction was carried out under mild conditions and tolerated a wide range of substrates, which provides a new and efficient strategy for the synthesis of sulfonic esters.