233751-87-6Relevant articles and documents
Metallated 2-alkenyl sulfoximines in asymmetric synthesis: Regio- and stereoselective synthesis of highly substituted oxabicyclic ethers and studies towards the total syntheses of the euglobals G1 and G2 and arenaran A
Reggelin, Michael,Gerlach, Matthias,Vogt, Melanie
, p. 1011 - 1031 (2007/10/03)
2-Cyclopentenyl- and 2-cyclohexenylmethyl sulfoximines can be converted into angular carbon-functionalised, highly substituted, isomerically pure (ds ± 98%) 2-oxabicyclo[3.3.0]octanes and 2-oxabicyclo[3.4.0]nonanes in high yields by a convenient one-pot sequence. Molecular frameworks such as these can be found in many biologically active natural products. In addition to the methodological work, we report on studies towards the total synthesis of the euglobals G1 and G2 and arenaran A.