233770-32-6

Basic information

• Product Name: 2-formyl-3-mesityl-1-tosylpyrrole
• Synonyms: 2-formyl-3-mesityl-1-tosylpyrrole
• CAS NO: 233770-32-6
• Molecular Weight: 367.469
• Mol File: 233770-32-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-formyl-3-mesityl-1-tosylpyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-formyl-3-mesityl-1-tosylpyrrole(233770-32-6)
• EPA Substance Registry System: 2-formyl-3-mesityl-1-tosylpyrrole(233770-32-6)

Safety Data

• Hazardous Substances Data: 233770-32-6(Hazardous Substances Data)

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 51985-30-9 4-Methyl-N-[(E)-3-phenyl-prop-2-en-(E)-ylidene]-benzenesulfonamide 
• 233770-17-7 3-iodo-2-styryl-1-tosylpyrrole 
• 233770-16-6 (E)-N-(4,4'-diethoxy-1-styrylbut-2-ynyl)-4-toluenesulfonamide 
• 137845-37-5 4-methyl-N-((1E,2E)-3-phenylallylidene)benzenesulfonamide 
• 5980-97-2 mesitylboronic acid 
• 233770-15-5 3-iodo-1-tosyl-1H-indole-2-carbaldehyde 

Relevant articles and documents

Studies of palladium-catalyzed coupling reactions for preparation of hindered 3-arylpyrroles relevant to (-)-rhazinilam and its analogues

Suzuki cross-coupling reactions of 3-pyrroleboronic acid derivatives with haloaromatics and the reverse process i.e., the coupling of 3-iodo(bromo)pyrroles with arylboronic acids have been investigated as a potential key step in the synthesis of (-)-rhazinilam and analogues. It was found that 3-iodo-2-formyl-1-tosylpyrroles efficiently coupled with a variety of arylboronic acids in the presence of PdCl2(dppf) as catalyst. This catalytic system is compatible with a broad spectrum of arylboronic acids - electron-rich, electron-poor, hindered, heterocyclic - which easily coupled with the pyrrole substrate.