23378-88-3 Usage
Description
3,5-Dichloro-2-hydroxybenzenesulfonyl chloride is an organic compound with the chemical formula C6H4Cl2O3S. It is a light beige to light brown powder and is used as a synthetic intermediate in the production of various chemical compounds.
Uses
Used in Pharmaceutical Synthesis:
3,5-Dichloro-2-hydroxybenzenesulfonyl chloride is used as a synthetic intermediate for the production of (1R,2R)-(+)-1,2-(3,3',5,5'-tetrachloro-2,2'-dihydroxydibenzenesulfonamido)-1,2-diphenylethane and (1R,2R)-(+)-1,2-(3,3',5,5'-tetrachloro-2,2'-dihydroxydibenzenesulfonamido)cyclohexane. These compounds have potential applications in the pharmaceutical industry.
Used in Analytical Chemistry:
3,5-Dichloro-2-hydroxybenzenesulfonyl chloride is used as a chromogenic system in a one-step kinetic method for the determination of 5'-nucleotidase. This application is valuable in the field of analytical chemistry for the detection and quantification of specific enzymes.
Check Digit Verification of cas no
The CAS Registry Mumber 23378-88-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,3,7 and 8 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 23378-88:
(7*2)+(6*3)+(5*3)+(4*7)+(3*8)+(2*8)+(1*8)=123
123 % 10 = 3
So 23378-88-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H3Cl3O3S/c7-3-1-4(8)6(10)5(2-3)13(9,11)12/h1-2,10H
23378-88-3Relevant articles and documents
WDR5-MYC INHIBITORS
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Paragraph 00492; 00539-00540; 01149-001150; 001254-001255, (2021/02/05)
Substituted N-phenyl sulfonamide compounds inhibit WDR5-MYC interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.
Enantioselective addition of diethylzinc to benzaldehyde catalyzed by chiral titanate complexes with helical ligands
Guo, Cheng,Qiu, Jun,Zhang, Xumu,Verdugo, Dawn,Larter, Martin L.,Christie, Ray,Kenney, Patrick,Walsh, Patrick J.
, p. 4145 - 4158 (2007/10/03)
Enantioselective alkylation of benzaldehyde with Et2Zn has been studied. This reaction is catalyzed by helical titanium complexes of tetradentate ligands and has been found to give good to excellent enantioselectivities.