23406-52-2

Basic information

• Product Name: (S)-3-Phenyl-2-butanone
• Synonyms: (3S)-3-Phenyl-2-butanone;(S)-3-Phenyl-2-butanone;[S,(+)]-3-Phenyl-2-butanone;Methyl[(S)-α-methylbenzyl] ketone
• CAS NO: 23406-52-2
• Molecular Formula: C₁₀H₁₂O
• Molecular Weight: 148.2
• Mol File: 23406-52-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 207.3±9.0 °C(Predicted)
• Appearance: /
• Density: 0.967±0.06 g/cm3(Predicted)
• CAS DataBase Reference: (S)-3-Phenyl-2-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-Phenyl-2-butanone(23406-52-2)
• EPA Substance Registry System: (S)-3-Phenyl-2-butanone(23406-52-2)

Safety Data

• Hazardous Substances Data: 23406-52-2(Hazardous Substances Data)

Upstream product

• 7782-24-3 (S)-2-Phenylpropionic acid 
• 87841-67-6 C₂₀H₂₄O 
• 100-44-7 benzyl chloride 
• 32123-84-5 3-phenylbut-3-en-2-one 
• 512176-91-9 benzyl 2-acetyl-2-phenylpropanoate 
• 769-59-5 3-phenyl-butan-2-one 
• 103-82-2 phenylacetic acid 
• 102-16-9 benzyl 2-phenylacetate 
• 512176-79-3 benzyl 3-oxo-2-phenylbutanoate 
• 103-79-7 1-phenyl-acetone 
• 1429767-28-1 4,4,5,5-tetramethyl-2-(3-phenylbut-1-en-2-yl)-1,3,2-dioxaborolane 

Downstream Products

• 26306-08-1 (S)-2-phenyl-butanone-⁽³⁾-oxime 
• 33484-95-6 2-Phenyl-3-methyl-3-pentanol 
• 33484-95-6 2-Phenyl-3-methyl-3-pentanol 
• 23406-53-3 ((R)-1,2-Dimethyl-allyl)-benzene 
• 119788-74-8 (2S*,3S*)-2-Hydroxy-2-methyl-1,3-diphenyl-1-butanon 
• 119788-73-7 (2R*,3S*)-2-Hydroxy-2-methyl-1,3-diphenyl-1-butanon 
• 119788-55-5 (2R,3S)-2-Methyl-1,3-diphenyl-2-trimethylsilanyloxy-butan-1-one 
• 119788-54-4 (2R*,3S*)-2-Methyl-1,3-diphenyl-2-(trimethylsilyloxy)-1-butanon 
• 119788-61-3 (2R,3S)-2-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-1,3-diphenyl-butan-1-one 
• 119788-60-2 (2R*,3S*)-2-(tert-Butyldimethylsilyloxy)-2-methyl-1,3-diphenyl-1-butanon 

Relevant articles and documents

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BVMO-catalysed dynamic kinetic resolution of racemic benzyl ketones in the presence of anion exchange resins

4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB was employed in the presence of a weak anion exchange resin to perform dynamic kinetic resolutions of racemic benzyl ketones with high conversions and good optical purities. Different parameters that affect to the efficiency of the enzymatic Baeyer-Villiger oxidation and racemisation were analyzed in order to optimize the activity and selectivity of the biocatalytic system. The Royal Society of Chemistry.

Selective Baeyer-Villiger oxidation of racemic ketones in aqueous-organic media catalyzed by phenylacetone monooxygenase

The enantioselective kinetic resolution of a set of racemic substituted 3-phenylbutan-2-ones employing phenylacetone monooxygenase (PAMO) in non-conventional media was performed. The studies have revealed the effects of a range of solvents on the biocatalytic properties of the biocatalyst. Also, the enzymatic oxidation of α-acetylphenylacetonitrile was performed using organic cosolvents. This has resulted in a dynamic kinetic resolution of this cyanoketone yielding enantiopure (R)-2-acetoxyphenylacetonitrile with moderate yields depending on the reaction conditions employed.