23412-22-8

Basic information

• Product Name: 4'-benzyloxycarbonyl-4'-demethylpodophyllotoxin
• Synonyms: 4'-benzyloxycarbonyl-4'-demethylpodophyllotoxin
• CAS NO: 23412-22-8
• Molecular Weight: 534.519
• Mol File: 23412-22-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4'-benzyloxycarbonyl-4'-demethylpodophyllotoxin(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-benzyloxycarbonyl-4'-demethylpodophyllotoxin(23412-22-8)
• EPA Substance Registry System: 4'-benzyloxycarbonyl-4'-demethylpodophyllotoxin(23412-22-8)

Safety Data

• Hazardous Substances Data: 23412-22-8(Hazardous Substances Data)

Upstream product

• 6559-91-7 4'-demethylepipodophyllotoxin 
• 501-53-1 benzyl chloroformate 
• 40505-27-9 4-demethylpodophyllotoxin 

Downstream Products

• 111275-47-9 1-O-(2-amino-2,6-dideoxy-α-D-glucopyranosyl)-4'-O-demethyl-1-epipodophyllotoxin 
• 111275-47-9 1-O-(2-amino-2,6-dideoxy-β-D-glucopyranosyl)-4'-O-demethyl-1-epipodophyllotoxin 
• 118190-50-4 1-β-<1L-(1,3/2,4,6)-6-amino-1,2,3-trihydroxycyclohexyloxy>-4'-O-demethyl-1-deoxypodophyllotoxin 
• 118190-50-4 (5R,5aR,9S)-9-((1R,2R,3R,4R,5S)-2-Amino-3,4,5-trihydroxy-cyclohexyloxy)-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 118190-49-1 (5R,5aR,9S)-9-((1R,2R,3S,4R,5S)-5-Amino-2,3,4-trihydroxy-cyclohexyloxy)-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 111275-66-2 1-O-(2,4,6-tri-O-acetyl-3-benzyloxycarbonylamino-3-deoxy-β-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 
• 99194-78-2 1-O-(3,4,6-tri-O-acetyl-2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 

Relevant articles and documents

ARYLTETRALIN LIGNANS FROM PODOPHYLLUM HEXANDRUM AND PODOPHYLLUM PELTATUM

Roots of Podophyllum hexandrum and P. peltatum contain the same range of ten aryltetralin lignans: podophyllotoxin, 4'-demethylpodophyllotoxin, α-peltatin, β-peltatin, desoxypodophyllotoxin, podophyllotoxone, isopicropodophyllone, 4'-demetyldesoxypodophyllotoxin, 4'-demethylpodophyllotoxone and 4'-demethylisopicropodophyllone, although the relative proportions are markedly different.The latter two compounds are previously unreported natural products, but 4'-demethylisopicropodophyllone may well be an artefact resulting from epimerization of 4'-demethylpodophyllotoxone.The peltatins have not previously been isolated from P. hexandrum.Key Word Index - Podophyllum hexandrum; P. peltatum; Podophyllaceae; aryltetralin; lignans; podophyllotoxin.

HUMAN TOPOISOMERASE II-TARGETING ORGANOPLATINUM COMPOUNDS

Some organoplatinum compounds have been synthesized. These organoplatinum compounds are designed to be human Topoisomerase II-targeting drugs.