23439-90-9

Basic information

• Product Name: (R)-2,2-dimethyl-1-phenylpropyl acetate
• Synonyms: (R)-2,2-dimethyl-1-phenylpropyl acetate
• CAS NO: 23439-90-9
• Molecular Weight: 206.285
• Mol File: 23439-90-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (R)-2,2-dimethyl-1-phenylpropyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2,2-dimethyl-1-phenylpropyl acetate(23439-90-9)
• EPA Substance Registry System: (R)-2,2-dimethyl-1-phenylpropyl acetate(23439-90-9)

Safety Data

• Hazardous Substances Data: 23439-90-9(Hazardous Substances Data)

Upstream product

• 3835-64-1 2,2-dimethyl-1-phenylpropan-1-ol 
• 108-24-7 acetic anhydride 
• 30070-63-4 meta-chlorobenzoic anhydride 
• 23406-58-8 (R)-(-)-4,4-dimethyl-3-phenylpentan-2-one 
• 100895-65-6 (-)-(S)-(1-chloro-2,2-dimethylpropyl)benzene 
• 563-63-3 silver(I) acetate 
• 64-19-7 acetic acid 
• 23439-91-0 2,2-dimethyl-1-phenyl-1-propanol 

Relevant articles and documents

Enantioselective acylations catalyzed by chiral phosphines

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PQXdpap: Helical Poly(quinoxaline-2,3-diyl)s Bearing 4-(Dipropylamino)pyridin-3-yl Pendants as Chirality-Switchable Nucleophilic Catalysts for the Kinetic Resolution of Secondary Alcohols

Helically chiral poly(quinoxaline-2,3-diyl)s bearing 4-(dipropylamino)pyridin-3-yl pendants at the 5-position of the quinoxaline ring (PQXdpap) exhibited high catalytic activities and moderate to high selectivities (up to s = 87) in the acylative kinetic resolution of secondary alcohols. The solvent-dependent helical chirality switching of PQXdpap between pure toluene and a 1:1 mixture of toluene and 1,1,2-trichloroethane enabled the preparation of either compound of a pair of enantiomerically pure alcohols (>99% ee) from a single catalyst.

Kinetic resolution of secondary alcohols by chiral dmap derivatives prepared by the Ugi multicomponent reaction

The kinetic resolution of secondary alcohols was examined by new chiral DMAP derivatives, which can readily be prepared by the Ugi multicomponent reaction in a one-pot operation. The initial screening of DMAP derivatives indicated that the catalyst bearing L-valine with an S configuration at the a-position of amide showed the best stereoselectivity factor. After the reaction conditions were optimized with (S,S)-4a in the kinetic resolution of secondary alcohols, various acyclic and cyclic secondary alcohols could be resolved with an s -factor of up to 12.