23443-10-9 Usage
General Description
Pyrido[1,2-a]pyrimidin-4-one is a heterocyclic chemical compound with a fused pyrimidine structure. It belongs to the group of alkaloids and is commonly found in natural sources such as plants and microorganisms. Pyrido[1,2-a]pyriMidin-4-one has potential biological activities and is used in the pharmaceutical industry for the development of new drugs. Its chemical structure and properties make it suitable for various medicinal applications, including anti-inflammatory, anti-tumor, and anti-bacterial activities. Pyrido[1,2-a]pyrimidin-4-one is a versatile compound with promising prospects for use in the field of medicine and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 23443-10-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,4,4 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 23443-10:
(7*2)+(6*3)+(5*4)+(4*4)+(3*3)+(2*1)+(1*0)=79
79 % 10 = 9
So 23443-10-9 is a valid CAS Registry Number.
23443-10-9Relevant articles and documents
Suzuki-Miyaura cross-coupling reactions of halo derivatives of 4H-pyrido[1,2-a]pyrimidin-4-ones
Molnar, Annamaria,Kapros, Anita,Parkanyi, Laszlo,Mucsi, Zoltan,Vlad, Gabor,Hermecz, Istvan
supporting information; experimental part, p. 6559 - 6565 (2011/11/05)
The palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of halo derivatives of 4H-pyrido[1,2-a]pyrimidin-4-one with (het)arylboronic acids allow easy access to (het)aryl and vinyl derivatives of this bicycle in good to excellent yields, even from chloro derivatives. The sequence of reactivity of the halogen in the different positions of the ring system was also investigated. 6-Phenyl-4H-pyrido[1,2-a]pyrimidin-4-one could be prepared by thermal cyclization of isopropylidene (6-phenylpyrid-2-ylamino)methylenemalonate, together with a small amount of 7-phenyl-1,4-dihydro-1,8-naphthyridin-4-one.
