234766-95-1

Basic information

• Product Name: Ethanone, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-phenyl-2-(4-pyridinyl)-
• CAS NO: 234766-95-1
• Molecular Formula: C19H25NO2Si
• Molecular Weight: 327.499
• Mol File: 234766-95-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-phenyl-2-(4-pyridinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-phenyl-2-(4-pyridinyl)-(234766-95-1)
• EPA Substance Registry System: Ethanone, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-phenyl-2-(4-pyridinyl)-(234766-95-1)

Safety Data

• Hazardous Substances Data: 234766-95-1(Hazardous Substances Data)

Upstream product

• 6919-61-5 N-methoxy-N-methylbenzamide 
• 117423-41-3 4-((tert-butyldimethylsilyloxy)methyl)pyridine 

Relevant articles and documents

Substituted imidazoles as glucagon receptor antagonists

A modestly active, nonselective triarylimidazole lead was optimized for binding affinity with the human glucagon receptor. This led to the identification of a 2- and/or 4-alkyl or alkyloxy substituent on the imidazole C4-aryl group as a structural determinant for significant enhancement in binding with the glucagon receptor (e.g., 41, IC50 = 0.053 μM) and selectivity (> 1000 ×) over p38 MAP kinase in this class of compounds.