23477-48-7Relevant articles and documents
Novel indole-N-glucoside, TA-1887 As a sodium glucose cotransporter 2 inhibitor for treatment of type 2 diabetes
Nomura, Sumihiro,Yamamoto, Yasuo,Matsumura, Yosuke,Ohba, Kiyomi,Sakamaki, Shigeki,Kimata, Hirotaka,Nakayama, Keiko,Kuriyama, Chiaki,Matsushita, Yasuaki,Ueta, Kiichiro,Tsuda-Tsukimoto, Minoru
, p. 51 - 55 (2014/02/14)
Inhibition of the renal sodium glucose cotransporter (SGLT) increases urinary glucose excretion (UGE) and thus reduces blood glucose levels during hyperglycemia. To explore the potential of new antihyperglycemic agents, we synthesized and determined the h
Sweet (hetero)aromatics: Glycosylated templates for the construction of saccharide mimetics
Wiebe, Christine,Schlemmer, Claudine,Weck, Stefan,Opatz, Till
, p. 9212 - 9214 (2011/10/04)
Mono- and diglycosylated aromatics and heteroaromatics may serve as building blocks for the construction of metabolically stable mimetics of oligosaccharides. Methods for their preparation from monosaccharidic precursors by direct C-glycosylation, dipolar cycloaddition or Larock cyclization are described.
Synthesis of 1-glycosyl derivatives of benzocamalexin
Humenik, Martin,Dzurilla, Milan,Kutschy, Peter,Solcaniova, Eva,Kovacik, Vladimir,Bekesova, Slavka
, p. 1657 - 1674 (2007/10/03)
The linear synthesis of 1-(β-o-glucopyranosyl)-, 1-(β-D- galactopyranosyl)-, 1-(β-D-mannopyranosyl)- and 1-(β-D-ribofuranosyl) benzocamalexin was elaborated from indoline as a starting compound and corresponding pentaacetylhexoses or 1-O-acetyl-2,3,5-tri-