2348-19-8Relevant articles and documents
Formation of potentially toxic carbonyls during oxidation of triolein in the presence of alimentary antioxidants
Damanik, Marini,Murkovic, Michael
, p. 2031 - 2035 (2017/10/26)
Abstract: A relation between oil uptake and cancer as well as induction of hepatic inflammation was shown earlier. It is discussed that the main oil oxidation products—hydroperoxides and carbonyls—might be the reason for the mentioned diseases. In this manuscript quantitative determination of aldehydes which are formed during oxidation of triolein—as a model substance—using the Rancimat 679 is described. The oxidation of 11?g of triolein is carried out at 120?°C sparging air with a flow of 20?dm3/h for 10?h. A series of aliphatic aldehydes starting from hexanal to decanal as well as decenal was identified by LC–MS/MS and quantified as DNPH derivatives. In addition, the total amount of carbonyls was determined. Based on the calibration with hexanal, all other dominant substances were in the similar concentration range with maximum concentrations of 1.6?μmol/cm3 of hexanal, 2.3?μmol/cm3 of heptanal, 2.5?μmol/cm3 of octanal, 3.2?μmol/cm3 of nonanal, 4.0?μmol/cm3 of decanal after 6?h. The total amount of carbonyls reached a maximum after 6?h being 27?μmol/cm3 for triolein without antioxidant. The results of this investigation will be a basis for further toxicological studies on oxidized oils.
1-(Carbazol-9-ylmethyl)benzotriazole Anion: A Formyl Anion Equivalent
Katritzky, Alan R.,Yang, Zhijun,Lam, Jamshed N.
, p. 2143 - 2147 (2007/10/02)
The title anion, readily available as its lithium derivative, smoothly reacts with a wide range of electrophiles to give well-characterized products which are easily hydrolyzed to the corresponding aldehydes in high overall yields.The method is compared with currently available routes.