23539-15-3Relevant articles and documents
99mTc imaging agents and methods of use
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Page/Page column 10, (2015/09/28)
An embodiment of the invention comprises method of imaging a target site comprising administrating ligand of Formula I complexed to 99mTc wherein R1 and R2 are independently an alkyl or cycloalkyl; R3 is and alk
99mTc IMAGING AGENTS AND METHODS OF USE
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Page/Page column, (2013/08/14)
An embodiment of the invention comprises a ligand of Formula I wherein R1 and R2 are independently an alkyl or cycloalkyl; R3 is and alkyl; X is CO or SO2; Y is (CH2)n, C6H4, (OC
Supramolecular catalysis of H/D exchange in pyruvate by macrocyclic polyamines involving a reactive iminium intermediate
Fenniri, Hicham,Dallaire, Carol,Funeriu, Daniel P.,Lehn, Jean-Marie
, p. 2073 - 2081 (2007/10/03)
The activity of a series of macrocyclic polyamines as catalysts for proton exchange has been investigated. Structural and physico-chemical studies demonstrate the ability of these receptors to recognize pyruvate, form a covalent iminium intermediate and catalyse H/D exchange at the CH3 position. The reaction follows Michaelis-Menten kinetics with a rate enhancement higher than 4.8 × 105 (kcat/kuncat). The process also represents a potential entry into the catalysis of aldol condensation reactions.