23583-46-2 Usage
Description
1-(3-O-acetyl-2-deoxy-5-O-tritylpentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione is a complex chemical compound derived from thymidine, a nucleoside that is a structural component of DNA. It features a pentofuranosyl group, an acetyl group, and a trityl group, along with a pyrimidine-2,4(1H,3H)-dione moiety. The presence of these functional groups suggests that this compound may be utilized in chemical synthesis or serve as a precursor to other compounds, with its specific properties and potential applications varying depending on the context of its study or use.
Uses
Used in Chemical Synthesis:
1-(3-O-acetyl-2-deoxy-5-O-tritylpentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione is used as an intermediate in chemical synthesis for the development of new compounds. Its unique structure, which includes a pentofuranosyl group, an acetyl group, and a trityl group, allows for further modification and functionalization, making it a valuable building block in the synthesis of various organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(3-O-acetyl-2-deoxy-5-O-tritylpentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione is used as a precursor for the development of potential therapeutic agents. Its structural similarity to thymidine, a key component of DNA, may make it a candidate for the design of novel drugs targeting DNA-related processes or diseases.
Used in Material Science:
1-(3-O-acetyl-2-deoxy-5-O-tritylpentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione's complex structure and functional groups may also find applications in material science, where it could be used to develop new materials with specific properties. For instance, its acetyl and trityl groups could be exploited to create materials with tailored chemical or physical characteristics, depending on the desired application.
Check Digit Verification of cas no
The CAS Registry Mumber 23583-46-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,5,8 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 23583-46:
(7*2)+(6*3)+(5*5)+(4*8)+(3*3)+(2*4)+(1*6)=112
112 % 10 = 2
So 23583-46-2 is a valid CAS Registry Number.
23583-46-2Relevant articles and documents
Exploring the potential of 3′-O-carboxy esters of thymidine as inhibitors of ribonuclease A and angiogenin
Ghosh, Kalyan S.,Debnath, Joy,Dutta, Palash,Sahoo, Bijaya K.,Dasgupta, Swagata
, p. 2819 - 2828 (2008/09/20)
In this study, compounds with a carboxy ester in lieu of the phosphate ester at the 3′-position have been employed to inhibit the ribonucleolytic activity of ribonuclease A (RNase A). Phosphates at the 3′-position of pyrimidine bases are well-known inhibitors of the protein. We have investigated the inhibition of RNase A by 3′-O-carboxy esters of thymidine. The compounds behave as competitive inhibitors with inhibition constants ranging from 42 to 95 μM. The mode of inhibition has also been confirmed by 1H NMR studies of the active site histidines of RNase A. Docking studies have further substantiated the experimental results. The compounds are also found to inhibit the ribonucleolytic activity of angiogenin, a homologous protein and potent inducer of blood vessel formation.
