23616-35-5

Basic information

• Product Name: 1,6-NAPHTHYRIDINE, 2,5-DICHLORO-
• Synonyms: 1,6-NAPHTHYRIDINE, 2,5-DICHLORO-;2,5-Dichloro-1,6-naphthyridine
• CAS NO: 23616-35-5
• Molecular Formula: C8H4Cl2N2
• Molecular Weight: 199.04
• Mol File: 23616-35-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 337.3±37.0 °C(Predicted)
• Appearance: /
• Density: 1.486
• PKA: 0.73±0.30(Predicted)
• CAS DataBase Reference: 1,6-NAPHTHYRIDINE, 2,5-DICHLORO-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-NAPHTHYRIDINE, 2,5-DICHLORO-(23616-35-5)
• EPA Substance Registry System: 1,6-NAPHTHYRIDINE, 2,5-DICHLORO-(23616-35-5)

Safety Data

• Hazardous Substances Data: 23616-35-5(Hazardous Substances Data)

Usage

General Description

1,6-NAPHTHYRIDINE, 2,5-DICHLORO- is a chemical compound with the molecular formula C10H5Cl2N. It is a naphthyridine derivative that contains two chlorine atoms on the 2 and 5 positions of the naphthyridine ring. 1,6-NAPHTHYRIDINE, 2,5-DICHLORO- is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in the production of dyes, pigments, and other specialty chemicals. 1,6-NAPHTHYRIDINE, 2,5-DICHLORO- is a white to light yellow crystalline solid that should be handled and stored with proper care and safety measures due to its potential hazards.

Upstream product

• 23616-31-1 1,6-naphthyridine-5(6H)-one 
• 23616-32-2 5-chloro-[1,6]naphthyridine 

Relevant articles and documents

Wnt SIGNALING INHIBITOR, COMPOSITION, AND COMPOUND AS USE THEREFOR

PROBLEM TO BE SOLVED: To provide an inhibitor for Wnt signaling route. SOLUTION: The present invention provides a compound represented by formula I, and a composition comprising the compound (X1-X8 independently represent CR4 or N; Y1 is H or C (R4)3; Y2 and Y3 independently represent H, halogen or C (R3)3; R1 and R2 independently represent H, halogen, C1-6 alkyl, quinolinyl or the like; R3s independently represent H, halogen, cyano, C1-6 alkyl or the like; R4s independently represent H, halogen, cyano, C1-6 alkoxy or the like). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

TUMOR BIOMARKERS AND USE THEREOF

Disclosed herein are biomarkers related to WNT signal transduction pathway, as well as methods and kits comprising the same. Further, the present disclosure relates to the use of the biomarkers in patient selection, companion diagnostics, and treatment of cancer.

COMPOUNDS FOR TREATMENT OF CANCER

The present invention relates to compounds as inhibitor of WNT signal transduction pathway, as well as a composition comprising the same. Further, the present invention relates to the use of the compounds in the treatment of cancer.