2363165-42-6

Basic information

• Product Name: rac-(1S,2R)-2-(2-methyl-4-(1-((1-(4-(pyridin-4-ylsulfonyl)phenyl)azetidin-3-yl)methyl)piperidin-4-yl)-1,2,3,4-tetrahydroisoquinolin-4-yl)cyclopentyl methylcarbamate
• CAS NO: 2363165-42-6
• Molecular Weight: 657.877
• Mol File: 2363165-42-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: rac-(1S,2R)-2-(2-methyl-4-(1-((1-(4-(pyridin-4-ylsulfonyl)phenyl)azetidin-3-yl)methyl)piperidin-4-yl)-1,2,3,4-tetrahydroisoquinolin-4-yl)cyclopentyl methylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: rac-(1S,2R)-2-(2-methyl-4-(1-((1-(4-(pyridin-4-ylsulfonyl)phenyl)azetidin-3-yl)methyl)piperidin-4-yl)-1,2,3,4-tetrahydroisoquinolin-4-yl)cyclopentyl methylcarbamate(2363165-42-6)
• EPA Substance Registry System: rac-(1S,2R)-2-(2-methyl-4-(1-((1-(4-(pyridin-4-ylsulfonyl)phenyl)azetidin-3-yl)methyl)piperidin-4-yl)-1,2,3,4-tetrahydroisoquinolin-4-yl)cyclopentyl methylcarbamate(2363165-42-6)

Safety Data

• Hazardous Substances Data: 2363165-42-6(Hazardous Substances Data)

Upstream product

• 140-29-4 phenylacetonitrile 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 624-83-9 methyl isocyanate 
• 285-67-6 Cyclopentene oxide 
• 6517-69-7 <1-benzylpiperidylidine-(4)>-phenylacetonitrile 
• 7254-21-9 N-benzyl-2-phenyl-2-(piperidin-4-yl)acetonitrile 

Relevant articles and documents

PIPERIDINES AS MENIN INHIBITORS

The present disclosure provides compounds represented by Formula (I): (Formula(I)) and the pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R2, R3a, R3b, A, G, X, and Y are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat a condition or disorder responsive to menin inhibition such as cancer.