236392-94-2

Basic information

• Product Name: Benzoic acid, 2-bromo-3-hydroxy-4,5-dimethoxy-, methyl ester
• CAS NO: 236392-94-2
• Molecular Formula: C10H11BrO5
• Molecular Weight: 291.098
• Mol File: 236392-94-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-bromo-3-hydroxy-4,5-dimethoxy-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-bromo-3-hydroxy-4,5-dimethoxy-, methyl ester(236392-94-2)
• EPA Substance Registry System: Benzoic acid, 2-bromo-3-hydroxy-4,5-dimethoxy-, methyl ester(236392-94-2)

Safety Data

• Hazardous Substances Data: 236392-94-2(Hazardous Substances Data)

Upstream product

• 79831-86-0 methyl 3-(benzyloxy)-4,5-dihydroxybenzoate 
• 26409-24-5 methyl 3-benzyloxy-4,5-dimethoxybenzoate 
• 99-24-1 methyl galloate 
• 1916-08-1 3-hydroxy-4,5-dimethoxybenzoic acid 
• 83011-43-2 3-hydroxy-4,5-dimethoxybenzoate 

Downstream Products

• 171565-80-3 (S)-(E)-2-<2-bromo-4,5-dimethoxy-3-(4-nitrobenzyloxy)-benzylidene>-3-(3,4,5-trimethoxybenzyl)butanolide 
• 171565-86-9 (R-Biar)-11-benzyloxy-4,13-dihydro-6,7,8,9,10-pentamethoxydibenzo<4,5:6,7>cycloocta<1,2-c>furan-1(3H)-one 
• 167759-92-4 2-bromo-4,5-dimethoxy-3-(4-nitrobenzyloxy)benzaldehyde 
• 171565-79-0 2-bromo-4,5-dimethoxy-3-(4-nitrobenzyloxy)benzyl alcohol 
• 1617-49-8 3,3',4-tri-O-methylellagic acid 
• 956031-02-0 methyl 8,10-dibenzyloxy-3,4,9-trimethoxy-6-oxo-6H-dibenzo[b,d]pyran-1-carboxylate 
• 956030-89-0 2'-bromo-5',6'-dimethoxy-3'-methoxycarbonylphenyl 2-bromo-3,4,5-trimethoxybenzoate 
• 956031-01-9 2'-bromo-5',6'-dimethoxy-3'-methoxycarbonylphenyl 2-bromo-3,5-dibenzyloxy-4-methoxybenzoate 
• 236392-95-3 4,5-dimethoxy-3-hydroxy-2-vinylbenzoic acid methyl ester 
• 171565-78-9 methyl 2-bromo-4,5-dimethoxy-3-(4-nitrobenzyloxy)benzoate 

Relevant articles and documents

Multi-functionalization of gallic acid towards improved synthesis of α- and β-DDB

The synthesis of mono-, di- and trisubstituted gallic acids and their ester with similar or different groups including different acetal and ketals is described. Regioselective bromination on two ortho-positions of methyl gallate, which is very crucial for many organic syntheses, was achieved in high yield and purity. The α- and β-DDB were synthesized in high overall yield and purity from the regioselective bromoderivatives.

Total Syntheses of the Metabolites of Schizandrin

The total syntheses of the metabolites of schizandrin were achieved.The tetracyclic lactone intermediates (13a-e) were prepared in optically pure form by the oxidative coupling reaction of the corresponding 3-benzyl-2-benzylidenebutyrolactones.Mukaiyama hydration of 13b afforded hydroxylactone (14), which was converted into SZ-M3 (4).The introduction of C6,7-diol moiety, which is common to the metabolites (4-11), was carried out by the successive double bond migration to 15a-e, lactone ring reduction ot the allylic diols (32a-e), and glycol formation.Then, reduction of the mesylates 33 completed the syntheses of the metabolites.