236406-22-7

Basic information

• Product Name: tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate
• Synonyms: tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate;1-Boc-4-(aMinoMethyl)-4-Methylpiperidine;4-AMinoMethyl-1-Boc-4-Met...;4-AMinoMethyl-1-Boc-4-Methylpiperidine;4-aMinoMethyl-1-t-butoxycarbonyl-4-Methylpiperidine
• CAS NO: 236406-22-7
• Molecular Formula: C₁₂H₂₄N₂O₂
• Molecular Weight: 228.334
• Mol File: 236406-22-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 304.8 °C at 760 mmHg
• Flash Point: 138.1 °C
• Appearance: /
• Density: 1.002
• Vapor Pressure: 0.000855mmHg at 25°C
• Refractive Index: 1.476
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate(236406-22-7)
• EPA Substance Registry System: tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate(236406-22-7)

Safety Data

• RIDADR: UN2811
• Hazardous Substances Data: 236406-22-7(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate is a chemical compound used in the synthesis of pharmaceuticals and other organic molecules. It is a derivative of piperidine and is often utilized as a building block for the creation of other complex compounds. tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate is a tertiary amine, meaning the nitrogen atom is attached to three alkyl groups. The tert-butyl group provides steric hindrance that can influence the reactivity and stability of the molecule. Overall, tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate is an important intermediate in organic synthesis with a variety of potential applications.

InChI:InChI=1/C12H24N2O2/c1-11(2,3)16-10(15)14-7-5-12(4,9-13)6-8-14/h5-9,13H2,1-4H3

Upstream product

• 530115-96-9 4-cyano-4-methylpiperidine-1-carboxylic acid tert-butyl ester 
• 189442-92-0 N-tert-Butoxycarbonyl-4-methyl-4-piperidine carboxaldehyde 
• 343788-67-0 4-carbamoyl-4-methylpiperidine-1-carboxylic acid tert-butyl ester 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 189442-87-3 ethyl tert-butyl 4-methylpiperidine-1,4-dicarboxylate 
• 236406-21-6 4-(hydroxymethyl)-4-methylpiperidine-1-carboxylic acid tert-butyl ester 
• 614730-89-1 4-methanesulfonyloxymethyl-4-methylpiperidine-1-carboxylic acid tert-butyl ester 
• 91419-52-2 1-tert-butoxycarbonyl-4-cyanopiperidine 

Relevant articles and documents

BROMODOMAIN INHIBITORS AND USES THEREOF

The present invention relates to compounds of formula (I): [INSERT FORMULA (1)] and to salts thereof, wherein R1, R2, Rc, and Rd have any of the values defined in the specification, and compositions and uses thereof. The compounds are useful as inhibitors of bromodomains. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various bromodomain-mediated disorders.

2′ Biaryl amides as novel and subtype selective M1 agonists. Part I: Identification, synthesis, and initial SAR

Biaryl amides were discovered as novel and subtype selective M1 muscarinic acetylcholine receptor agonists. The identification, synthesis, and initial structure-activity relationships that led to compounds 3j and 4c, possessing good M1 agonist potency and intrinsic activity, and subtype selectivity for M1 over M2-5, are described.

CANNABINOID RECEPTOR LIGANDS

There are disclosed compounds of the formula I: or a pharmaceutically acceptable salt of the compound, which exhibit anti-inflammatory and immunomodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds.