23656-73-7

Basic information

• Product Name: 1-Piperidinepropanamide, N-(4-methoxyphenyl)-
• CAS NO: 23656-73-7
• Molecular Formula: C15H22N2O2
• Molecular Weight: 262.352
• Mol File: 23656-73-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Piperidinepropanamide, N-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinepropanamide, N-(4-methoxyphenyl)-(23656-73-7)
• EPA Substance Registry System: 1-Piperidinepropanamide, N-(4-methoxyphenyl)-(23656-73-7)

Safety Data

• Hazardous Substances Data: 23656-73-7(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 19313-87-2 N-(4-methoxyphenyl)-β-chloropropanamide 
• 54872-83-2 3-piperidin-1-yl-propionyl chloride 
• 104-94-9 4-methoxy-aniline 
• 26371-07-3 1-piperidinepropionic acid 

Relevant articles and documents

LiCl-promoted amination of β-methoxy amides (γ-lactones)

An efficient and mild method has been developed for the amination of β-methoxy amides (γ-lactones) including natural products michelolide, costunolide and parthenolide derivatives by using lithium chloride in good yields. This reaction is applicable to a wide range of substrates with good functional group tolerance. Mechanism studies show that the reactions undergo a LiCl promoted MeOH elimination from the substrates to form the corresponding α,β-unsaturated intermediates followed by the Michael addition of amines.