236752-17-3

Basic information

• Product Name: Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-1-methyl-
• CAS NO: 236752-17-3
• Molecular Formula: C32H32N4O7
• Molecular Weight: 584.629
• Mol File: 236752-17-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-1-methyl-(236752-17-3)
• EPA Substance Registry System: Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-1-methyl-(236752-17-3)

Safety Data

• Hazardous Substances Data: 236752-17-3(Hazardous Substances Data)

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 2140-73-0 1-methylinosine 
• 58-63-9 Inosine 

Downstream Products

• 661471-80-3 5'-O-(4,4'-dimethoxytrityl)-1-methyl-2'-O-[[(triisopropylsilyl)oxy]methyl]inosine 

Relevant articles and documents

The Synthesis of 2′-O-[(Triisopropylsilyl)oxy] methyl (TOM) Phosphoramidites of Methylated Ribonucleosides (m1G, m2G, m22G, m1I, m3U, m4C, m6A, m62A) for Use in Automated RNA Solid-Phase Synthesis

The straightforward synthesis of eight methylated ribonucleoside phosphoramidites is described. These building blocks allow for incorporation of the naturally occuring nucleosides 1-methylguanosine (m1G), N 2-methylguanosine (m2G), N2N 2-dimethylguanosine (m22G), 1-methylinosine (m1I), 3-methyluridine (m3U), N4- methylcytidine (m4C), N6-methyladenosine (m6A), and N6,N6-dimethyladenosine (m62A) into oligoribonucleotides by automated RNA solid-phase synthesis. In all cases, the ribose 2′-hydroxyl group of the building blocks is masked by the recently introduced [(triisopropylsilyl)oxy]methyl (TOM) group.